A Rapid Self-Pumping Organohydrogel Dressing with Hydrophilic Fractal Microchannels to Promote Burn Wound Healing

The research article discusses a self-pumping organohydrogel dressing with hydrophilic fractal microchannels that can rapidly drain excessive exudates from burn wounds, enhancing efficiency by approximately 30 times compared to a pure hydrogel. This dressing promotes burn wound healing by reducing the dermal cavity by about 42.5%, accelerating blood vessel regeneration by approximately 6.6 times, and hair follicle regeneration by around 13.5 times, compared to the commercial dressing (Tegaderm). The dressing is created through a creaming-assistant emulsion interfacial polymerization approach, which forms the hydrophilic fractal hydrogel microchannels in the self-pumping organohydrogel. The study was conducted on a murine burn wound model.