Bilateral Burning Palmoplantar Lesions

    December 2023 in “ Cutis ”
    Delaney D Ding
    Image of study
    TLDR The woman was diagnosed with lichen sclerosus, a rare skin condition, after initial misdiagnosis and ineffective treatments.
    A 59-year-old woman with a history of type 2 diabetes, liver dysfunction, thyroid nodules, vitamin deficiencies, and diffuse androgenic alopecia presented with hypopigmented, ivory papules and plaques on her palms and soles, which were initially misdiagnosed as plaque psoriasis. Despite treatment with high-potency topical steroids and biologics, her condition did not improve. A punch biopsy revealed lichen sclerosus (LS), a rare chronic inflammatory skin condition often underdiagnosed and characterized by porcelain-white atrophic plaques. LS is associated with autoimmune diseases and can present with debilitating symptoms, though it is rare for it to affect the palms and soles without genital involvement.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Clascoterone (Winlevi) Update for Canada

      in Treatment  16 upvotes 2 years ago
      Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 7 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  96 upvotes 3 weeks ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

      community C’est terrible - at my wits end

      in Female  440 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

    Similar Research

    5 / 1000+ results