Effectiveness of Baricitinib for Nasal, Genital, and Beard Hair Regrowth in Patients with Severe Alopecia Areata: 12-Month Outcomes from a Prospective Observational Study

    November 2025 in “ SKIN The Journal of Cutaneous Medicine ”
    Justin Ko, Karan Lal, Michelle Tarbox, Susan Ball, Angelina Sontag, Firas Dabbous, Mary Kate Ladd, Klaudia Kornalska, Najwa Somani, Jerry Shapiro
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    TLDR Baricitinib significantly regrows hair in nasal, genital, and beard areas for severe alopecia areata.
    A 12-month study with 254 adults with severe alopecia areata found that baricitinib, a JAK inhibitor, led to significant hair regrowth in nasal (52%), genital (44%), and beard areas (53%). Participants also reported reduced bothersomeness of hair loss, initially rated high. These results suggest baricitinib's potential for treating hair loss beyond the scalp, offering a holistic approach for severe AA.
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