Autosomal Recessive Woolly Hair Syndrome: A Series of Eight Patients in an Indian Population

    November 2025 in “ Skin Health and Disease ”
    Vijay Kumar Somani, Anirudh Somani, Ashwini Annabathula
    Studysummary This case series describes eight instances of autosomal recessive woolly hair in an Indian population over the past 12 years, detailing their clinical presentation, hair traits, and treatment response.
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    Research cited in this study 6

    1. Association of Topical Minoxidil With Autosomal Recessive Woolly Hair/Hypotrichosis Caused by LIPH Pathogenic Variants JAMA Dermatology · 2020
    2. Topical Minoxidil and Tretinoin Combined with an Oral Vitamin D Analog as a Treatment for Woolly Hair Dermatologic Therapy · 2016
    3. The Twisting Tale of Woolly Hair: A Trait with Many Causes Journal of medical genetics · 2015
    4. Clinical Effects of Non-Ablative and Ablative Fractional Lasers on Various Hair Disorders: A Case Series of 17 Patients Journal of Cosmetic and Laser Therapy · 2013
    5. Disruption of P2RY5, an Orphan G Protein–Coupled Receptor, Underlies Autosomal Recessive Woolly Hair Nature genetics · 2008
    6. Human Hair Growth Deficiency Is Linked to a Genetic Defect in the Phospholipase Gene LIPH Science · 2006