Prevalence and Risk Factors Associated With the Occurrence of Autoimmune Diseases in Patients With Alopecia Areata

September 2021 in “ DOAJ (DOAJ: Directory of Open Access Journals) ”

K Chanprapaph, T Mahasaksiri, C Kositkuljorn, K Leerunyakul, P Suchonwanit

alopecia areata autoimmune diseases autoimmune thyroid disease vitiligo systemic lupus erythematosus nail abnormalities atopic diseases AA AD thyroid disease lupus

TLDR Alopecia areata patients often have other autoimmune diseases, especially women with nail issues or atopic diseases.

This study investigated the prevalence and risk factors for autoimmune disease (AD) comorbidities in 615 patients with alopecia areata (AA). It found that 12.4% of these patients had comorbid ADs, with autoimmune thyroid disease being the most common (6.8%), followed by vitiligo (2.4%) and systemic lupus erythematosus (2.0%). Significant risk factors for coexisting ADs included female sex, nail abnormalities, and atopic diseases. Specifically, nail abnormalities were linked to autoimmune thyroid disease, atopic diseases predicted vitiligo, and female sex and family history of AD were predictors for systemic lupus erythematosus. The findings suggested that identifying these risk factors could help in screening AA patients for potential AD comorbidities.

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