Androgenetische Alopezie beim Mann . Male androgenetic alopecia
August 2002
in “Zeitschrift für Hautkrankheiten”
TLDR Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.
This document from 2002 discusses male androgenetic alopecia (AGA), which is a DHT-dependent process that leads to progressive miniaturization of sensitive hair follicles. The role of Type 2-5α-Reductase in the intrafollicular conversion of testosterone to DHT is highlighted, and the genes responsible for AGA are still unknown. The document also discusses the potential for new therapeutic options with non-toxic and selective inhibitors, as well as selective androgen receptor blockers. The role of Caspases in the process of hair follicle miniaturization is also emphasized.
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