An Asian traditional herbal complex containing Houttuynia cordata Thunb, Perilla frutescens Var. acuta and green tea stimulates hair growth in mice
December 2017
in “BMC Complementary and Alternative Medicine”
TLDR The Asian herbal mix with Houttuynia cordata, Perilla frutescens, and green tea helped grow hair in mice.
In the 2017 study, a traditional Asian herbal complex containing Houttuynia cordata Thunb, Perilla frutescens Var. acuta, and green tea was tested on C57BL/6 mice for its hair growth-promoting effects. The mice were divided into groups and treated with either 200 mg/kg or 400 mg/kg of the herbal complex, a negative control, or a positive control with finasteride. Results showed significant hair growth in the herbal complex-treated groups, with the 400 mg/kg group showing the most pronounced effects. Histological examinations indicated an increased number of hair follicles and diameter, while Western blot analysis revealed higher levels of IGF-1 and lower levels of TGF-β1, suggesting the herbal complex's potential to promote hair growth by modulating these growth factors. The study concluded that the herbal complex could be effective in hair regeneration, with no significant side effects observed, but noted the need for further research due to limitations such as the small sample size and lack of data on topical application.
View this study on bmccomplementmedtherapies.biomedcentral.com →
Cited in this study
research The promotion of hair regrowth by topical application of a Perilla frutescens extract through increased cell viability and antagonism of testosterone and dihydrotestosterone
Applying an extract from Perilla frutescens helps hair grow and fights the effects of hair loss hormones.
research Enhancement of Human Hair Growth UsingEcklonia cavaPolyphenols
Ecklonia cava polyphenols help increase human hair growth and reduce hair loss.
research Androgenetic Alopecia: An Evidence-Based Treatment Update
Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.
research Prevention and treatment of alopecia areata with quercetin in the C3H/HeJ mouse model
research Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men
Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.
research Hair growth and rejuvenation: An overview
The document concludes that minoxidil and finasteride are proven for hair growth, herbal remedies show promise, but more research is needed to confirm their effectiveness.
research Human hair growth enhancement in vitro by green tea epigallocatechin-3-gallate (EGCG)
Green tea component EGCG could potentially promote human hair growth.
research The effect of tripeptide-copper complex on human hair growth in vitro
A tripeptide-copper complex may help hair grow by increasing cell growth and decreasing cell death.
research Molecular mechanisms of androgenetic alopecia
AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.
research Investigation of topical application of procyanidin B-2 from apple to identify its potential use as a hair growing agent
Apple-derived procyanidin B-2 can safely promote hair growth in men.
research Treatment of Hair Loss
Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.
research Finasteride in the treatment of men with androgenetic alopecia
Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.
research MOUSE MODELS FOR THE STUDY OF HUMAN HAIR LOSS
Mice are useful for researching human hair loss and testing treatments, despite some differences between species.
research The Therapeutic Use of Topical Minoxidil
Minoxidil effectively treats hair loss, with better results in women.
research Topical tretinoin for hair growth promotion
Tretinoin may help hair growth and works better when combined with minoxidil.