Alopecia Areata Secondary to the Use of Leflunomide in Patients with Rheumatoid Arthritis: A Case Report and Literature Review

    December 2015 in “ Medwave ”
    María Ignacia Molina Molina, Carmen María Pinochet Paiva, José Ignacio Quezada Morales
    Image of study
    TLDR Leflunomide can cause severe hair loss in some rheumatoid arthritis patients.
    Leflunomide, a commonly prescribed DMARD for rheumatoid arthritis, was effective in suppressing disease factors but had notable side effects, including diarrhea, nausea, rash, and alopecia. Although alopecia was a known side effect, cases of alopecia universalis were rare. The document presented a case from the Regional Hospital of Talca and reviewed the literature on leflunomide's use, highlighting the need for awareness of its potential to cause severe hair loss in some patients.
    Discuss this study in the Community →

    Research cited in this study

    8 / 8 results

    Related Community Posts Join

    6 / 1000+ results

      community Alopecia Areata Question

      in Treatment  2 upvotes 4 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

      community Olumiant alternative for Alopecia Areata?

      in Treatment  1 upvotes 2 years ago
      A user with alopecia areata is considering treatment options like injections or Olumiant but is concerned about cost and whether delaying treatment will lead to permanent hair loss. They are seeking alternative treatments that are more affordable for a college student.

      community Hairloss all over body and head

      in Treatment  2 upvotes 1 month ago
      A 25-year-old experiencing hair thinning all over the body and head, despite using minoxidil and having low vitamin D levels, is advised to seek a second opinion from a dermatologist specializing in hair loss. The likely diagnosis is diffuse alopecia areata, which may require treatment with a JAK inhibitor.

      community Aminexil, Nanoxidil, Stemoxydine and Kopexil. Anyone use them?

      in Question  1 upvotes 8 years ago
      Aminexil, nanoxidil, stemoxydine, and kopexil are discussed as alternatives to minoxidil for hair growth, with concerns about dependence. Minoxidil is noted for its effectiveness in transitioning hair growth phases, but dependence is mainly linked to androgenic alopecia.

    Similar Research

    5 / 1000+ results