The Additive Effect of Platelet-Rich Plasma in the Treatment of Actively Bleeding Peptic Ulcer

    May 2021 in “ Clinical Endoscopy ”
    Waseem M. Seleem, Amr Shaaban Hanafy
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    TLDR Platelet-rich plasma treatment is more effective and cost-efficient than epinephrine for healing bleeding peptic ulcers, with fewer complications and rebleeding cases.
    The study involved 80 patients with peptic ulcer bleeding and compared the effectiveness of platelet-rich plasma (PRP) and epinephrine in treating the condition. Both treatments achieved immediate hemostasis, but rebleeding occurred in 5% of the PRP group and 20% of the epinephrine group. Hemoglobin levels significantly increased in the PRP-treated group, with full recovery occurring in 60.5% of patients compared to 31.3% in the epinephrine group. The study concluded that PRP was efficient, cost-effective, and had no complications, bringing about sustained and complete healing of bleeding peptic ulcers.
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