Clinical Characteristics and Treatment of Acne with Sensitive Skin

This study on 170 Chinese subjects found that over 58% of acne patients also have sensitive skin, which is linked to increased transepidermal water loss, decreased epidermal thickness, and enlarged blood vessels. Two treatment groups were compared: one with oral isotretinoin and topical lincomycin gel, and another with additional topical barrier repair cream and light therapy. After 56 days, both groups showed significant reductions in acne lesions, but the combination treatment group had greater improvements in inflammatory and total lesions, as well as lower Investigator Global Assessment scores. The study highlights the importance of addressing both acne and skin sensitivity, recommending barrier repair creams and light therapy for enhanced treatment effectiveness.