A Randomized, Placebo-Controlled Trial of 1% Topical Minoxidil Solution in the Treatment of Androgenetic Alopecia in Japanese Women

In this randomized, placebo-controlled trial, researchers investigated the efficacy of 1% topical minoxidil solution in the treatment of androgenetic alopecia in Japanese women. The trial included 280 Japanese female patients with androgenetic alopecia who were administered either 1% topical minoxidil or placebo for 24 weeks. The primary efficacy variable was the mean change from baseline in non-vellus hair count/cm(2). The results showed that the mean change was significantly higher in the 1% topical minoxidil group compared to the placebo group. Secondary variables, including investigators' assessments and patients' self-assessments, also showed significant improvement in the 1% topical minoxidil group. The patients tolerated the treatment well without significant adverse effects.