Minoxidil in the Treatment of Alopecia: Literature Review on Efficacy and Safety

November 2025 in “ Revista Foco ”

Adriely Almeida Vilhena, Sarah Ingrid Pinto Santos

Minoxidil alopecia perifollicular vasodilation growth factor modulation dermatitis microneedling Rogaine

From the encyclopedia

An essential vasodilator with some anti-androgenic effects

technique to create small wounds in skin to activate collagen production and hair growth

Studysummary This study reviewed the effectiveness and safety of Minoxidil for treating alopecia and found that concentrations of 2% to 5% effectively promoted hair growth, especially when combined with other therapies like microneedling, despite manageable local side effects.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

4 / 4 results

Efficacy of 5% Topical Minoxidil Versus 5 Mg Oral Biotin Versus Topical Minoxidil and Oral Biotin on Hair Growth in Men: Randomized, Crossover, Clinical Trial

research Efficacy of 5% Topical Minoxidil Versus 5 Mg Oral Biotin Versus Topical Minoxidil and Oral Biotin on Hair Growth in Men: Randomized, Crossover, Clinical Trial

April 2024 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia”

Using both minoxidil and biotin together increased hair growth more than using either one alone.

research New Target for Minoxidil in the Treatment of Androgenetic Alopecia

August 2023 in “Drug Design Development and Therapy”

This study found that minoxidil may treat androgenetic alopecia by affecting hormonal and enzymatic pathways, identifying new targets CYP17A1 and CYP19A1 and demonstrating its inhibition of androgenic receptors.

research Androgenetic Alopecia: The Use of Minoxidil and Its Adverse Effects

July 2021 in “Research, Society and Development”

This study reviewed literature on the adverse effects of Minoxidil in treating androgenetic alopecia, highlighting common reactions like hypertrichosis, scalp irritation, and contact dermatitis, while noting less frequent cardiovascular symptoms, concluding that the treatment is effective and generally well-tolerated.

research Minoxidil: A Comprehensive Review

16 citations , June 2021 in “Journal of Dermatological Treatment”

This study reported that while topical minoxidil exhibits hair regrowth in androgenetic alopecia, oral minoxidil 5 mg/day was more effective than topical forms after six months, with low doses also potentially effective for women and other hair loss types.