40 citations
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October 2002 in “Endocrinology” In this study, synthetic vitamin D3 analogs stimulated hair growth and formation of normal hair follicles in nude mice, unlike the natural form 1,25 dihydroxyvitamin D3.
June 2024 in “The Journal of Nutritional Biochemistry” This study found that 1,25-dihydroxyvitamin D3 promotes hair growth and regeneration in mice by prolonging the anagen phase and counteracting DHT's inhibitory effects, suggesting its potential therapeutic role for androgenetic alopecia.
27 citations
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September 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that relatively low concentrations of 1,25(OH)2D3 stimulated human hair follicle and fiber growth, while higher concentrations inhibited growth in a whole-organ culture system.
July 2013 in “International Society of Hair Restoration Surgery” This commentary explores the potential of 1α,25-dihydroxyvitamin D3 in enhancing hair regeneration by affecting dermal papilla cells, but reports no new experimental findings.
November 2023 in “Elsevier eBooks” This study found that vitamin D receptor mutations lead to hair follicle alopecia due to impaired cyclic regeneration, which is distinct from vitamin D receptor effects on epidermal keratinocytes that largely depend on 1,25-dihydroxyvitamin D.