Response to Minimum Requirements for Reporting Clinical Trials Evaluating the Therapeutic Potential of Platelet-Rich Plasma

August 2020 in “ Journal of The American Academy of Dermatology ”

Lu Yin, Katerina Svigos, Kumar Sukhdeo, Anthony D. Ho, Kristen Lo Sicco, Jerry Shapiro

platelet-rich plasma PRP androgenetic alopecia hair growth split-scalp design placebo randomized controlled trials

Studysummary This letter discusses the variability in platelet-rich plasma preparation for androgenetic alopecia treatment and highlights that different methods yield varied platelet concentrations but not significant differences in growth factor secretion per platelet.

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research Minimum Requirements for Reporting Clinical Trials Evaluating the Therapeutic Potential of Platelet-Rich Plasma

7 citations , August 2020 in “Journal of The American Academy of Dermatology”

This letter comments on a randomized controlled trial by Shapiro et al that found no significant benefits of platelet-rich plasma compared to placebo for male androgenetic alopecia, highlighting issues with PRP protocol variations.

research Heterogeneity in Amount of Growth Factors Secreted by Platelets in Platelet-Rich Plasma Samples from Alopecia Patients

8 citations , August 2020 in “Experimental dermatology”

This study observed that platelet-rich plasma samples from female patients show significant variability in growth factor secretion, which may influence the inconsistent clinical response in alopecia treatment.

research Evaluation of Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia: A Randomized Controlled Trial

33 citations , July 2020 in “Journal of The American Academy of Dermatology”

In this study, PRP increased hair density in areas treated for androgenetic alopecia, but there was no significant difference when compared to placebo-treated areas.

Growth Factor Concentrations in Platelet-Rich Plasma for Androgenetic Alopecia: An Intra-Subject, Randomized, Blinded, Placebo-Controlled, Pilot Study

research Growth Factor Concentrations in Platelet-Rich Plasma for Androgenetic Alopecia: An Intra-Subject, Randomized, Blinded, Placebo-Controlled, Pilot Study

13 citations , January 2020 in “Experimental Dermatology”

This pilot clinical trial suggests that platelet-rich plasma (PRP) treatment may increase hair density in patients with androgenetic alopecia, though outcomes varied between patients.

research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study

136 citations , January 2013 in “International Journal of Trichology”

This study found that adding microneedling to minoxidil treatment significantly improved hair growth in men with androgenetic alopecia compared to minoxidil alone across all assessed measures.