Baldness and Testicular Cancer: The EPSAM Case-Control Study

January 2016 in “ International Journal of Andrology ”

Giovenale Moirano, Daniela Zugna, Chiara Grasso, Patrizia Lista, Libero Ciuffreda, Nereo Segnan, Franco Merletti, Lorenzo Richiardi

baldness androgen activity body hairiness testicular cancer seminomas non-seminomas androgen sensitivity androgen levels androgen metabolism

Studysummary In this study, researchers found an inverse association between baldness and testicular cancer, suggesting androgen activity may influence cancer risk.

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Research cited in this study

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research Androgenetic Alopecia and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis

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research Baldness, Acne, and Testicular Germ Cell Tumors

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This study found that male pattern baldness and a history of severe acne were inversely associated with testicular germ cell tumors, while taller height showed a positive association.

research Androgens and Hair Growth

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This review discusses the role of androgens in hair follicle regulation and suggests that a better understanding could enhance treatments for conditions like hirsutism and alopecia, but does not present new findings.

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This review discusses the definition, pathogenesis, diagnosis, and management of hirsutism and reports no new clinical results.

Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia

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People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.