Influence of External Factors on Hair Cortisol Concentrations

May 2016 in “ General and Comparative Endocrinology ”

Theresa Salaberger, Marlon Millard, Samy El Makarem, Erich Möstl, Viktoria Grünberger, Reinhild Krametter‐Frötscher, Thomas Wittek, Rupert Palme

hair cortisol cortisol glucocorticoid skin

Studysummary This study found that hair cortisol concentrations in sheep were significantly increased by extensive brushing or dexamethasone treatment, suggesting that external factors may affect its reliability as a chronic stress measure.

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research Short Communication: Factors Affecting Hair Cortisol Concentrations in Lactating Dairy Cows

118 citations , October 2014 in “Journal of Dairy Science”

This study found that in lactating Holstein cows, hair from the tail switch, which grows faster and is more sensitive to cortisol changes, is ideal for measuring hair cortisol levels.

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In this study, hair from forearms showed higher cortisol levels than hair from lower legs, suggesting a localized cortisol response in hair.

research Hair Analysis Provides A Historical Record Of Cortisol Levels In Cushing's Syndrome

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This study found that hair cortisol levels were significantly higher in patients with Cushing's Syndrome compared to healthy controls, suggesting hair analysis can provide historical information on cortisol exposure.

research Human Hair Follicles Display a Functional Equivalent of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Synthesize Cortisol

489 citations , June 2005 in “The FASEB Journal”

This study found that human scalp hair follicles can respond to corticotropin releasing hormone stimulation similarly to the classical HPA axis, including up-regulating cortisol production and activating neuroendocrine feedback loops.

research In Vitro Metabolism of Progesterone by Canine Hair Follicle Cells

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In this study, dermal fibroblasts in the head of beagle dogs metabolized the highest amount of progesterone, primarily into cortisol, while dermal papilla cells mainly produced 5α-pregnane-3,20-dione and cortisol.