Regulation of Itch-Induced Scratching by Nucleus Accumbens Dopamine Receptor-Expressing Neurons

    Jagat Narayan Prajapati, Nila Pattaliparambil Babu, Debstuti Basu, Dipak Sahare, Dadasaheb M. Kokare, Arnab Barik
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    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study found that distinct neurons in the nucleus accumbens lateral shell regulate scratching behavior differently; D1R neurons promote scratching while D2R neurons help stop it, with elevated dopamine levels during chronic itch potentially enhancing persistent scratching.
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