Kaposi Varicelliform Eruption in a 26-Year-Old Man with Pemphigus Vulgaris

    January 2015 in “ Indian Dermatology Online Journal
    Rita Vora, AbhishekP Pilani, NidhiB Jivani, RahulKrishna S Kota
    Studysummary This case report highlights the successful treatment of Kaposi varicelliform eruption in a pemphigus vulgaris patient using intravenous acyclovir, alongside antibiotics, resulting in healing of skin lesions with scarring.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    A 26-year-old man with pemphigus vulgaris developed Kaposi varicelliform eruption (KVE), presenting with high fever and multiple fluid-filled lesions. Examination revealed umbilicated vesicular lesions, severe facial edema, and patchy hair loss. Blood and pus cultures identified Staphylococcus aureus, and histopathology suggested herpes infection. The patient was treated with intravenous acyclovir, piperacillin-tazobactam, and linezolid, leading to healing with varicelliform scars. KVE, often misdiagnosed due to its similarity to underlying dermatoses, is a life-threatening viral infection requiring prompt antiviral and antibiotic treatment. Awareness and early recognition are crucial for effective management.
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