This article hypothesizes that thymoma with aplastic anemia may result from abnormal autoimmune CD8+ T lymphocytes produced by the thymoma, potentially leading to other cytotoxic T-cell-mediated autoimmune diseases.
January 2025 in “Figshare” In this case study, a 17-month-old girl experienced sudden hair depigmentation during septic shock hospitalization, suggesting systemic stress as a potential trigger for pediatric canities subita associated with diffuse alopecia areata.
January 2025 in “Figshare” This case report describes a 17-month-old girl who experienced sudden hair whitening during septic shock, suggesting systemic stress may trigger canities subita in young children and highlighting the need to distinguish it from congenital pigment dilution syndromes.
December 2025 in “Skin Appendage Disorders” This case report, one of the youngest on record, suggests that systemic stress might trigger pediatric sudden hair graying linked with diffuse alopecia areata, emphasizing the need to differentiate it from congenital silvery hair syndromes due to their distinct prognosis and treatment options.
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July 2017 in “Clinical Reviews in Allergy & Immunology” This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.
