Update on the Therapeutic Role of Metformin in the Management of Polycystic Ovary Syndrome: Effects on Pathophysiologic Process and Fertility Outcomes

    February 2025 in “ Women s Health ”
    K. Brand, Ulrike Gottwald‐Hostalek, Aimee Andag‐Silva
    Studysummary This paper reports that while metformin may improve fertility outcomes and reduce miscarriage rates in women with PCOS, its efficacy can differ depending on the specific treatment combination used.
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    Research cited in this study 4

    1. Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome Fertility and Sterility · 2023
    2. The Efficacy of 24-Month Metformin for Improving Menses, Hormones, and Metabolic Profiles in Polycystic Ovary Syndrome The Journal of Clinical Endocrinology & Metabolism · 2018
    3. Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan BMC Medicine · 2010
    4. ACOG Practice Bulletin No. 108: Polycystic Ovary Syndrome Obstetrics & Gynecology · 2009

    Related research 3

    1. Reconsidering PCOS Etiology, Diagnosis, Clinical Subgroups, and Subgroup-Specific Treatments Endocrine and metabolic science · 2024
    2. Polycystic Ovarian Syndrome: Current Understanding of Pathogenesis, Diagnosis, and Treatment Meditsinskiy sovet = Medical Council · 2021
    3. Screening for Diabetes in Women with Polycystic Ovary Syndrome Canadian Medical Association Journal · 2007