Three Months Extended-Release Microspheres Prepared by Multi-Microchannel Microfluidics in Beagle Dog Models

    August 2021 in “ International Journal of Pharmaceutics ”
    Ju Han Kim, Choong-Min Ryu, Chan Hee Chon … Seong Jin Jeong
    Studysummary This study demonstrated that finasteride-loaded PLGA microspheres created using a novel microfluidic device exhibit extended drug release in beagle dogs, with modifications allowing for release up to 3 months.
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    Research cited in this study 4

    1. Experimental, Molecular Docking Investigations and Bioavailability Study on the Inclusion Complexes of Finasteride and Cyclodextrins Drug Design Development and Therapy · 2017
    2. Assessment of the Usefulness of Dihydrotestosterone in the Diagnostics of Patients with Androgenetic Alopecia Postepy Dermatologii I Alergologii · 2014
    3. Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia Archives of Dermatology · 2010
    4. Preparation of Novel Polymeric Microspheres for Controlled Release of Finasteride International Journal of Pharmaceutics · 2007

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    1. Three Months Extended-Release Microspheres Prepared by Multi-Microchannel Microfluidics in Beagle Dog Models International Journal of Pharmaceutics · 2021