Jak1 Signaling Is Involved in the Induction of Mechanical Alloknesis in Atopic Dermatitis

    November 2025 in “ Biomedicines
    Ying Zuo, Sumika Toyama, Motoki Morita, Qiaofeng Zhao, Eriko Komiya, Soichiro Yoshikawa, Mitsutoshi Tominaga, Kenji Takamori
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    Studysummary This study found that the JAK1 inhibitors baricitinib and abrocitinib significantly reduced mechanical alloknesis in a murine model of atopic dermatitis, whereas the JAK2 inhibitor AZ960 had no effect.
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