Hypersomatotropism in Three Cats Without Concurrent Diabetes Mellitus

    Jon M. Fletcher, Christopher Scudder, Matti Kiupel, Hannah N. Pipe‐Martin, Patrick Kenny, Panagiotis Mantis, Joe Fenn, Ken Smith, Robert V. Blair, Luke Granger, Stijn Niessen
    Studysummary This case series reports three cats diagnosed with hypersomatotropism due to GH-secreting pituitary adenomas without concurrent diabetes mellitus, highlighting the potential for underdiagnosis in non-diabetic cats.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The document described three cases of hypersomatotropism in cats without concurrent diabetes mellitus, highlighting that this condition could occur in non-diabetic cats and might be underdiagnosed. All cases involved pituitary enlargement and increased IGF-1 concentrations, supporting the diagnosis. The study suggested that the current IGF-1 cutoff value might be too high, potentially leading to underdiagnosis. It emphasized the need for increased awareness and screening for hypersomatotropism in cats, regardless of their diabetic status, to allow for earlier detection and intervention, potentially preventing or delaying acromegaly and diabetes mellitus.
    Discuss this study in the Community →