MCMV Infection Lowers the Threshold for the Development of Clinical GvHD After Allogeneic Bone Marrow Transplantation

November 2004 in “ Blood ”

Mohammad Sohrab Hossain, John D. Roback, Edmund K. Waller

Studysummary This study found that CMV infection in a mouse model of allogeneic transplantation was associated with increased allo-reactive T cell expansion and exacerbated graft-versus-host disease, highlighting the need for effective GvHD prophylaxis and treatment.

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