Brachioradial Pruritus: Treatment with Topical Capsaicin

This review discusses neuropathic pruritus, detailing its clinical presentations and management strategies, but reports no new clinical results.

This study found that serlopitant may reduce pruritus intensity compared to placebo in patients with chronic pruritus of unknown origin, though evidence is of low certainty and effects on other outcomes are unclear.

This study suggests that TRPV3 may play a key role in dry skin-related itch, indicating potential for TRPV3 antagonists in treating pruritus resistant to histamine H1R antagonists.

This study observed an association between intense itching in anterior chest keloids and an increased density of nerve fibers in the epidermis, alongside elevated expression of the pruritus mediator substance P, though no difference was found in Langerhans cells related to pruritus, location, or region.

In this study, researchers observed that intractable pruritus in anterior chest keloid lesions is linked to increased intraepidermal nerve fibre density and elevated expression of substance P, without differences in Langerhans cells across different keloid regions.