High-Frequency (22-MHz) Ultrasound for Assessing the Depth of Basal Cell Carcinoma Invasion
January 2021
in “
Skin Research and Technology
”
TLDR High-frequency ultrasound effectively measures basal cell carcinoma depth.
The study evaluated the effectiveness of high-frequency ultrasound (HFUS) in assessing the depth of basal cell carcinoma (BCC) invasion by comparing ultrasound images of 83 lesions from 67 patients with histopathological findings. The results showed a strong correlation (r = 0.9744, P < .001) between HFUS and histopathological measurements, with HFUS demonstrating a sensitivity of 96%, specificity of 84%, and accuracy of 91% for measuring deep tumor margins. Factors such as basophilic degeneration of collagen and dense inflammatory changes affected measurements. The study concluded that HFUS was effective in localizing deep tumor margins in BCC, making it a valuable tool for selecting therapeutic approaches and evaluating surgical sites.
