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    Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort

    November 2018 in “ Antimicrobial agents and chemotherapy (Print) ”
    George R. Thompson, Charles R. Krois, Verena K. Affolter … Stephen D. White
    Studysummary This study found that fluconazole was associated with telogen effluvium in both a rat model and human patients, although retinoic acid levels were not identified as a causal factor.
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    Research cited in this study 7

    1. Hair Pull Test: Evidence-Based Update and Revision of Guidelines Journal of The American Academy of Dermatology · 2016
    2. Endogenous Retinoids in the Hair Follicle and Sebaceous Gland Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2011
    3. Towards Dissecting the Pathogenesis of Retinoid-Induced Hair Loss: All-Trans Retinoic Acid Induces Premature Hair Follicle Regression by Upregulation of Transforming Growth Factor-β2 in the Dermal Papilla Journal of Investigative Dermatology · 2005
    4. Alopecia Associated with Fluconazole Therapy Annals of Internal Medicine · 1996
    5. Alopecia Associated with Fluconazole Therapy Annals of Internal Medicine · 1996
    6. Alopecia Associated with Fluconazole Therapy Annals of internal medicine · 1995
    7. Binding of Steroid Hormones by the 105,000 x g Supernatant Fraction from Homogenates of Rat Skin and Variations During the Hair Cycle Journal of Biological Chemistry · 1972