HLT Megathread on HMI-115 (key takeaways in comments)
Research/Science 1/23/2023
HMI-115 prolactin receptor antagonist diffuse thinning telogen effluvium prolactin receptor signaling Phase I trials androgenetic alopecia DHT hair follicle PRL receptors endometriosis HopeMed Inc. Bayer hair transplants serum prolactin PRLR hyperprolactinemia Wnt inhibition alopecia areata androgens DKK1 WNT pathway IL-6 TGFbeta catagen Mucuna pruriens curcumin Gamma Linolenic Acid Evening primrose oil phytoestrogenic
HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
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