Pelage Announces Positive Results of Phase 2a Trials for PP405 Update 6/17/2025
PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.
View this post in the Community →
Similar Community Posts Join
6 / 232 resultscommunity Dr. Gary Linkov has just released a video talking about PP405.
PP405 shows promising results for hair density improvement, potentially outperforming Minoxidil in a shorter time. However, its public release is expected around 2029/2030, and its cost and availability remain uncertain.
community Minoxidil alone, 4 months consistent usage
Minoxidil 5% foam was used twice daily for 4 months, resulting in visible hair regrowth. Users discussed adding finasteride for better long-term results, with concerns about its side effects and alternatives like breezula and clascoterone.
community I'm sad I now lost enough hair I can only hide with a hat now
A 21-year-old is experiencing significant hair loss and considering treatments like dutasteride, minoxidil, and possibly a hair transplant. Others share their experiences with finasteride, scalp micropigmentation, and hair transplants, discussing the emotional impact and offering support.
community The DEFINITIVE cure for hairloss
The conversation humorously suggests using immunosuppressants like ciclosporine and oral minoxidil for hair regrowth, with a satirical plan involving hair transplants from family members. It highlights the side effects and impracticality of such treatments, emphasizing the post's satirical nature.
community "Hair Follicle Stem Cells are quiescent 99% of the time and permanently reside in the hair follicle"
Hair follicles are mostly dormant but can be reactivated with treatments like minoxidil, finasteride, and microneedling. A new drug, PP405, shows promise for hair regrowth but may not be available until 2027-2028.
community Does finasteride works forever as long as you take it?
Finasteride can maintain hair for many years, but its effectiveness may decrease over time. Some switch to dutasteride or add minoxidil for better results, with side effects like libido changes and ED discussed.
Related Research
6 / 18 results
research Recent Advances in Drug Development for Hair Loss
New treatments for hair loss show promise with advanced therapies and better targeting.
research Moxibustion Improves Ovarian Function Based on the Regulation of the Androgen Balance
Moxibustion may help improve ovarian function by changing androgen levels.
research Abstracts from the 17th Congress of the European Society for Dermatology and Psychiatry
The congress showed that psychological therapy can help skin condition patients, social media affects acne stigma, education improves atopic dermatitis, and patient satisfaction in dermatology is high, especially with good doctor engagement.
research Review of the 2024 American Academy of Dermatology Annual Meeting
New treatments for skin conditions show promise, especially Coacillium® for hair growth in young people with alopecia areata.
research Trichoscopy: Usefulness in Diagnosing Hair Loss in Adult Female Patients
Trichoscopy is a helpful and quick method to identify different types of hair loss in women.
research Hair Loss: An Epidemiologic Approach
Hair loss affects 20% of people, more in men and those over 35, and is often associated with a sensitive scalp.