DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!
    Research/Science 2/5/2025

    At a glance
    In this educational post, the primary subjects mentioned are
    💊 Dutasteride (oral) 0.5mg - 2.5mg once per day
    Minoxidil (topical or oral) 5% topical or 0.25mg - 5mg per day
    💊 Pioglitazone (oral) 15mg - 30mg once per day
    💧 Clobetasol Propionate (topical) 0.05% once per day
    💧 Calcipotriol (topical) 0.005% once per day
    Ketoconazole (shampoo) 2% 4 times a week
    💊 Doxycycline (oral) 200 mg once or twice a day
    the tone is 😐 neutral.

    Other terms

    DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

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      in Research  830 upvotes 8 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Minoxidil For 2 Years, What is this?

      in Treatment  111 upvotes 8 months ago
      The user has experienced significant hair thinning despite using 2.5 mg minoxidil for 2 years. Other users suggest adding finasteride or dutasteride and consulting a dermatologist for a proper diagnosis.

      community 7 years minoxidil user. Is this the Time for HT ?

      in Progress Pictures  46 upvotes 1 year ago
      A 25-year-old has used minoxidil for 7 years, finasteride for 2 years, oral minoxidil and dutasteride for 3 months, and also tried microneedling and nizoral. They are considering a hair transplant but are concerned about being a good candidate due to potential retrograde alopecia.

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      in Chat  46 upvotes 2 years ago
      How diffuse unpatterned alopecia (DUPA) is not an invitation to self-diagnose oneself with aggressive AGA and that seeking a specialized dermatologist may help people experiencing hair loss. Treatment options discussed include topical clobetasol propionate, oral minoxidil, and discontinuing finasteride.

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