Is regrowth on an androgen receptor blocker possible?
    Chat 4/20/2024

    At a glance
    In this question or advice post, the primary subjects mentioned are
    ๐Ÿ’ง RU58841 (topical) 2x daily 2.5 months
    ๐Ÿ’Š Finasteride (oral) 1mg 1x daily 1 month
    ๐Ÿ’Š Minoxidil (oral) 2.5mg 1x daily 2.5 months
    ๐Ÿ’ง Minoxidil (topical) over a year
    ๐Ÿ’Š Dutasteride (oral)
    โ€ข Microneedling 1.0-1.5mm weekly
    the tone is ๐Ÿ˜ neutral.

    Other terms

    RU and Pyri block androgen receptors to prevent hair loss but may also hinder hair regrowth since they prevent testosterone, which can stimulate hair growth, from binding to these receptors. The user is questioning if this understanding is correct.
    View this post in the Community โ†’

    Similar Community Posts Join

    5 / 1000+ results

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  449 upvotes 2 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Why is dht bad for scalp hair but good for hair on the rest of body?

      in Satire  109 upvotes 1 year ago
      The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  136 upvotes 7 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Pyrilutamide for 16 weeks, with some progress

      in Progress Pictures  40 upvotes 1 year ago
      User gained hair with topical minoxidil and finasteride, then experienced shedding after starting pyrilutamide. After 12 weeks, new hairs grew and existing hairs thickened, hoping for more improvement in a year.

    Related Research

    6 / 1000+ results