Tretinoin vs. micro-needling: what increases sulfotransferase activity more?
Research/Science 7/3/2025

At a glance

In this research discussion post, the primary subjects mentioned are

• Tretinoin

💧 Microneedling (topical) 0.8 mm

the tone is 😐 neutral.

Other terms

Tretinoin and microneedling both enhance hair growth through different mechanisms, with microneedling being considered safe for long-term use. Optimal microneedling needle length varies, but 0.8 mm is suggested for hair growth, and a Dermastamp is recommended to avoid skin damage.

View this post in the Community →

Similar Community Posts Join

5 / 1000+ results

community Microneedling, some people seem to permanently lost their hair. Confused

in Microneedling 35 upvotes 5 months ago

Microneedling can aid hair regrowth but poses risks like permanent hair loss if not done properly. Combining it with minoxidil, finasteride, and tretinoin, while ensuring proper sterilization and technique, is crucial for safety and effectiveness.

community Comprehensive Microneedling Guide

in Microneedling 291 upvotes 3 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community Back again with a 17 month update. (Fin/Min doing the heavy lifting, occasional 0.5mm microneedling, and Nizoral for scalp health) - Angles are not identical but whatever - Expecting and hoping to be back to pre-hairloss hairline within 6 months from now.

in Progress Pictures 393 upvotes 1 year ago

The conversation is about a user's 17-month progress in treating hair loss using finasteride, minoxidil, occasional 0.5mm microneedling, and Nizoral. The user reports significant hairline recovery and aims to achieve a pre-hair loss hairline within the next 6 months.

community 48 days of Fin, Min, and Dermaroller

in Progress Pictures 1747 upvotes 1 year ago

The user has been using finasteride for hair loss for 2-3 years, and added 5% topical minoxidil and daily 1.5mm dermarolling to their routine 50 days ago, which resulted in significant hair growth. The user recommends dermarolling along with minoxidil and finasteride for better results.

community Considering Quitting Topical Min

in Treatment 1 week ago

The user is considering stopping topical minoxidil due to lack of improvement in hair growth and is exploring alternatives like oral minoxidil, topical finasteride, and tretinoin. They are hesitant about oral finasteride and dutasteride, and are open to trying oral minoxidil if available, despite concerns about potential heart-related side effects.