Can I make a DIY Topical metformin? 1/11/2026
The conversation is about using DIY topical metformin for hair loss. A user tried it without success, and it was not combined with microneedling.
View this post in the Community →
Similar Community Posts Join
5 / 5 resultscommunity TCA 35% chemical peel, don't try this shit at home.
The conversation discusses using a TCA 35% chemical peel on the scalp to potentially improve hair growth by addressing fibrosis and enhancing the effectiveness of topical treatments. The user also mentions trying microneedling and other methods like topical metformin and dutasteride for hair regrowth.
community Topical finasteride in Europe?
The conversation discusses using topical finasteride as an alternative to oral medication for hair loss, with mentions of minoxidil, microneedling, ketoconazole shampoo, and other treatments. A user shares their experience with topical finasteride and other treatments, noting improved hair density.
community 2026 Hairloss Nuclear Stack Update
A user shared an extensive hair loss treatment regimen including dutasteride, minoxidil, tadalafil, RU58841, microneedling, and various topical and oral supplements. Responses varied, with some suggesting the regimen is excessive and others offering additional advice or expressing skepticism about its practicality and effectiveness.
community Topical Anti-Androgen users. What are y’all using currently? And what do you believe has the best chance of being approved? Or best results?
RU58841 is considered effective by some users, but finasteride and minoxidil are commonly used with varying dosages to manage side effects. Users report different experiences with treatments like pyrilutamide, fluridil, and RU58841, with some seeing results and others not.
community Wtf have we been doing for the last 30 years
Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.
Related Research
6 / 6 results
research Topical Metformin In Dermatology: A Narrative Review Of Efficacy And Formulation Approaches
This review evaluates existing research on topical metformin for skin conditions, reporting promising outcomes such as improved wound healing, melasma, psoriasis, acne, and alopecia, with innovative formulations like hydrogels and lipid nanoparticles enhancing its cutaneous delivery while minimizing systemic exposure.
research Cosmetic Approach for Men
This chapter reviews differences in dermatological treatments and conditions between male and female patients, particularly noting the impacts of sex steroids on various skin processes, but presents no new clinical findings.
research Current best evidence in pigmentary dermatology
In a randomized phase 2b clinical trial, oral ritlecitinib significantly reduced facial vitiligo area scores in patients with active nonsegmental vitiligo compared to placebo, with a favorable safety profile observed over 48 weeks, suggesting its potential as an effective treatment option (Ezzedine et al., 2023).
research Decoding Hyperpigmentation from Biological Mechanisms to Actives with Clinically Proven Topical Efficacy: A Narrative Review
This review provides an analysis of topical treatments with clinically proven efficacy for managing hyperpigmentation and concludes that the most effective approach is using combined therapies that target multiple aspects of skin pigmentation physiology.
research Female type of adult acne: Physiological and psychological considerations and management
This review discusses the distinct clinical and psychological aspects of adult female acne and reports no new clinical results, highlighting the need for a comprehensive management approach.
research Acne and acneiform eruptions
This book reviews the various types of acne and acneiform conditions, as well as their treatment options, with expert insights from multiple fields.