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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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Shedding or receding even more?
Journals / Progress Pictures The user experienced hair shedding after using finasteride and topical minoxidil since August 2024, and briefly adding oral minoxidil in early 2025. They suspect the shedding might be due to the oral minoxidil, a bad batch of finasteride, or a normal shedding cycle, and are also experiencing an itchy scalp and acne. -
Help deciding: Preventive finasteride now (NW2-3) vs. waiting for visible changes? (28M with family history)
Finasteride A 28-year-old male with a family history of baldness is deciding whether to start finasteride now or wait for visible hair changes. He is considering starting finasteride immediately to proactively address potential hair loss. -
1.4 years on finasteride, only lately have signs of improvement been showing
Progress Pictures The user noticed hair density improvement after 1.4 years on finasteride, with additional use of minoxidil on the temples. Other users discussed various treatments like dutasteride, estrogen, and hair transplants, sharing personal experiences and advice. -
Is this regrowth? My doctor took these photos and said I looked better.
Satire The conversation humorously discusses an extensive and exaggerated hair loss treatment regimen, including finasteride, dutasteride, minoxidil, pyrilutamide, RU58841, and various other therapies. Despite the numerous treatments, the effectiveness is questioned, and the user humorously considers adding more minoxidil. -
3 year progress thinning crown - 0.25 fin daily
Progress Pictures The user experienced significant hair maintenance using 0.25mg daily finasteride and minoxidil foam, with minimal side effects. They recommend oral finasteride for better results, especially for the crown area. -
3 month update on min. Added keto shampoo. Startinf dut
General The user started using topical and oral Minoxidil in December 2024, added ketoconazole shampoo in February 2025, and began using topical Dutasteride mixed with Minoxidil. The ketoconazole shampoo stopped scalp itchiness, but the hairline looks the same, with existing hairs appearing frail and thin.
New Featured Research
Hair root sonication washing impact on nuclei counts
The study investigated the impact of sonication washing on the persistence of nuclei in hair roots, which is crucial for DNA extraction. Hair roots with fewer than 50 visible nuclei were primarily used to assess changes in nuclei count after sonication in Terg-a-zyme™. The study found that sonication might reduce the number of nuclei available for DNA extraction and short tandem repeat (STR) typing, particularly in hair roots with fewer nuclei. For laboratories focusing solely on nuclear DNA analysis, a less aggressive washing method, such as low-speed vortexing in saline followed by an ethanol rinse, is recommended to preserve nuclei.
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New in research
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Clinical Efficacy of Microneedle Combined with 5% Minoxidil Solution and Finasteride in the Treatment of Androgenetic Alopecia in Males
Combining microneedling with Minoxidil and Finasteride greatly improves hair growth and reduces hair loss in men.
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Analyzing Efficacy of Low-Dose Oral Minoxidil, Topical Minoxidil, and Platelet-Rich Plasma with Topical Minoxidil Combination in Patients with Androgenetic Alopecia: A Randomized Controlled Observer Blinded Trial
Combining PRP with topical minoxidil is most effective for hair growth in androgenetic alopecia.
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Polynucleotides as a Novel Therapeutic Approach in Androgenetic Alopecia: An Analysis of Effectiveness and Safety
Polynucleotides effectively promote hair regrowth in androgenetic alopecia without serious side effects.
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Therapeutic Applications of Hair Follicle Transplantation Beyond Hair Restoration
Hair follicle transplantation can help treat wounds, sweating, odor, and skin conditions beyond just restoring hair.
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Assessing the Safety of Topical Minoxidil Through Disproportionality Analysis of FAERS Reports
Topical minoxidil may cause more side effects than currently listed, needing updated safety information.
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Unhealthy Diet and Lifestyle Factors Linked to Female Androgenetic Alopecia: A Community-Based Study from Jidong, China
Unhealthy diet and lifestyle choices may increase the risk of hair loss in women.
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The Retinoic Acid-Related Orphan Receptor Alpha May Be Highly Involved in the Regulation of Seasonal Hair Molting
RORA plays a key role in controlling seasonal hair molting by affecting hair follicle cell activity.
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Caffeine as an Active Ingredient in Cosmetic Preparations Against Hair Loss: A Systematic Review of Available Clinical Evidence
Caffeine may help with hair loss, but more research is needed.
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Insights Into the Peripheral Nature of Persistent Sexual Dysfunction Associated With Post-Finasteride, Post-SSRI, and Post-Accutane Syndromes: Lessons Learned From a Case Study
Peripheral treatments showed some improvement in sexual dysfunction, but central symptoms remain challenging.