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New in community
- Featured Community Post
Diffuse hair loss and scalp biopsies
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
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2 years on fin and amazed by the results
Finasteride/Dutasteride Finasteride significantly improved hair density and reduced hair loss for the user over two years, with plans to switch to dutasteride for long-term benefits. The user experienced no shedding or side effects and obtained finasteride through a private prescription in the UK. -
3 months in, fin 1mg/Day + min 5%/2xDay
Progress Pictures The user shared progress pictures after 3 months of using finasteride 1mg daily and minoxidil 5% twice daily, showing significant hair regrowth, especially at the temples. The discussion includes positive feedback on the results and tips on managing hair care while using these treatments. -
I'm so tired of people telling me to get over the fact that I'm balding at 18
Chat An 18-year-old is dealing with early hair loss and feels unsupported. They have started oral minoxidil and are considering finasteride but are worried about side effects due to high testosterone levels. -
FINALLY stopped shedding constantly after 1 year on 5ar inhibitors!! Moral of the story: Just wait
Chat After using finasteride for 7 months and dutasteride for 5 months, the user experienced a significant reduction in hair shedding and scalp itchiness. They advise patience with hair loss treatments and suggest focusing on a good haircut and reducing stress. -
5MG finasteride everyday June 1st 2024 - October 7th 2024
Progress Pictures The user has been using 1.25 mg of finasteride daily since June 2024 to promote hair regrowth and thickness, considering switching to dutasteride if results are unsatisfactory. They are hesitant to add minoxidil due to cost and potential side effects but have seen some progress with finasteride alone. -
Does finasteride/dutasteride reverse aging?
Chat Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.
New Featured Research
The molecular anatomy of cashmere goat hair follicle during cytodifferentiation stage
This study provides a detailed molecular analysis of cashmere goat hair follicle development during the cytodifferentiation stage using single-cell RNA sequencing (scRNA-seq). By examining 4,995 cells from Shaanbei white cashmere goats, researchers identified nine distinct cell populations, including cortex/cuticle, inner root sheath, and medulla, which are crucial for hair follicle morphogenesis. The study highlights the roles of transcription factors like GATA3, LEF1, and PRDM1, and processes such as autophagy and ferroptosis in hair follicle development. These findings offer insights into hair follicle morphogenesis and suggest strategies for improving cashmere fiber quality, with implications for breeding programs and the cashmere industry. The study involved three fetuses from three pregnant female goats, ensuring ethical compliance.
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New in research
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Long-Term Outcomes of Intravenous Corticosteroid Pulse Therapy for Rapidly Progressive Alopecia Areata: A Single-Center Retrospective Analysis of 106 Cases and Evaluation of a Scoring System for Extended Periods
Intravenous corticosteroid therapy is effective for long-term hair regrowth in alopecia areata, and a scoring system helps predict treatment success and relapse.
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Effects of Oxytocin Receptor Agonists on Hair Growth Promotion
OXTR agonists may promote hair growth and be effective for treating hair loss.
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CGF Therapy: Bridging Androgenetic Alopecia Observations to Psoriasis Treatment via IL-17 Pathway
CGF therapy may effectively treat psoriasis by reducing inflammation.
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Comparative Evaluation of Efficacy and Safety of Topical Methotrexate With Tretinoin Versus Betamethasone With Tretinoin in Patients of Alopecia Areata: A Prospective Randomized Double-Blind Study
Topical methotrexate is more effective and as safe as betamethasone for treating alopecia areata.
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Synergistic Phytochemical and Pharmacological Actions of Hair Rise Microemulsion: A Novel Herbal Formulation for Androgenetic Alopecia and Hair Growth Stimulation
Hair RiseTM microemulsion effectively promotes hair growth and treats hair loss better than standard treatments.
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Red And Green LED Light Therapy: A Comparative Study In Androgenetic Alopecia
Red LED therapy is more effective than green LED for improving hair growth in androgenetic alopecia.
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Platycladus Orientalis Leaf Extract Promotes Hair Growth Via Non-Receptor Tyrosine Kinase ACK1 Activation
Platycladus orientalis leaf extract helps hair grow by activating certain proteins.
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Evaluation of the Relationship Between Serum G Protein-Coupled Estrogen Receptors (GPER-1) Levels and the Severity and Duration of the Disease in Patients with Androgenetic Alopecia: A Case-Control Study
Higher GPER-1 levels are linked to more severe and shorter-duration androgenetic alopecia, suggesting GPER-1 as a potential treatment target.
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Fusarium sp. Strain K-23 Alleviates Salt Stress in Arabidopsis thaliana Through Its Root Hair Growth-Promoting Effect
Fusarium sp. strain K-23 helps Arabidopsis plants grow better in salty soil by promoting root hair growth.