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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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M27 need opinions on where I’m at and what options I could look at
General A 27-year-old is experiencing hair thinning and receding, currently using finasteride and planning to start minoxidil. They seek advice on hairline treatment options, including styling, PRP, peptides, and micro-needling. -
30M Need advice – is there still hope? (Currently on oral min + fin + mesotherapy)
General A 30-year-old is seeking advice on hair loss treatment, currently using oral minoxidil, finasteride, mesotherapy, and a supplement. They are experiencing shedding and are anxious about the effectiveness of the treatment, asking if they should continue or consider other options like topicals or microneedling. -
16 years later - Before and After
Progress Pictures A user shared their 16-year hair loss journey using finasteride and minoxidil, noting slow hair thinning despite a family history of severe balding. They switched from topical to oral minoxidil but stopped for personal reasons, experiencing no significant side effects from finasteride. -
17M - Seeking advice regarding hairloss, thinning and white hair
General A 17-year-old experiencing hair loss, thinning, and white hair seeks advice on effective treatments. They have started using shampoo and conditioner but have not seen improvement and are open to product suggestions. -
Do mens shampoo for hair loss help with balding?
Research/Science Shampoos, including those with ketoconazole, may offer mild benefits for hair health but are not effective for stopping hair loss or balding. Effective treatments for hair loss include finasteride and minoxidil, often used together, while shampoos are generally not on the scalp long enough to impact hair follicles significantly. -
96 days on oral min/fin progress?
Is this regrowth? The user has been using oral minoxidil and finasteride daily for 96 days and has noticed progress in hair regrowth, particularly on the crown. Suggestions include continuing the treatment, adding micro-needling, and possibly using tretinoin and dutasteride.
New Featured Research
Using the Mechanisms of Action Involved in the Pathogenesis of Androgenetic Alopecia to Treat Hair Loss
The document reviews the pathogenesis and treatment of androgenetic alopecia (AGA), emphasizing the roles of genetic and androgenic factors, particularly dihydrotestosterone (DHT) and androgen receptors, in hair follicle miniaturization. Current FDA-approved treatments, Minoxidil and Finasteride, are effective but require lifelong use. New pharmacological therapies targeting AGA's mechanisms, such as growth factors like IGF-1 and VEGF, are explored for potentially more effective treatments. Combining drugs has shown better outcomes, as demonstrated in studies where combinations like Minoxidil and Finasteride significantly improved hair growth. A study with 40 men using a combined topical treatment (TH07) showed promising results, with 52% experiencing dense hair growth. Overall, these treatments are well-tolerated, with no significant adverse effects reported.
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New in research
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Hyperandrogenism Insulin Resistance-Acanthosis Nigricans Syndrome in a Female Adolescent with Migraine: A Case Report
Early diagnosis and treatment of endocrine disorders like HAIR-AN syndrome can improve outcomes in adolescents.
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Amitriptyline-Induced Telogen Effluvium in a Patient with Cervical Disc Prolapse: A Case Report
Amitriptyline can cause temporary hair loss, which stops after discontinuing the drug.
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Dermatological Alterations Induced by Gynecological Hormonal Imbalances: Acne, Hirsutism, and Alopecia
Hormonal imbalances can cause acne, excess hair growth, and hair loss in women, needing combined medical and emotional care.
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Effects of GLP-1 Receptor Agonists on Hair Loss and Regrowth: A Systematic Review
GLP-1 receptor agonists may cause hair loss, but regrowth is rare.
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Psoriasis and Alopecia: Unveiling the Links
Psoriasis patients are more likely to develop alopecia areata due to complex autoimmune interactions.
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Exosome-Based Therapies for Androgenetic Alopecia: Mechanisms, MicroRNAs, and Clinical Prospects
Exosome therapy could be a promising new way to treat hair loss.
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Associations Between GLP-1 Receptor Agonists and Alopecia: A Multi-Center Retrospective Analysis and Public Interest Trends
GLP-1 receptor agonists may increase the risk of a specific type of hair loss called androgenetic alopecia.
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Prevalence and Hormonal Profiling of Secondary Amenorrheic Patients Presenting to a Fertility Clinic – An Observational Study
Hyperprolactinemia is the most common cause of secondary amenorrhea, followed by drug use.
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Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss
Women with hair loss often have deficiencies in iron, vitamins, minerals, and lower thyroid function, suggesting the need for nutritional and hormonal treatment.