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Diffuse hair loss and scalp biopsies
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
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4 months fin + 6 months minoxidil
Progress Pictures A 21-year-old shared progress pictures showing hair regrowth after using finasteride (1mg daily) for 4 months and minoxidil (topical, 1ml daily) for 6 months, with no significant side effects. The user experienced initial shedding but now reports no hair loss when running fingers through hair. -
5 month hair progress on fin+min
Progress Pictures The user shared their 5-month hair progress using oral finasteride and minoxidil, reporting positive results with minimal side effects. They use a chewable 2-in-1 product from Hims for convenience. -
[24M] 4 month update oral min/fin
Progress Pictures The user reported good progress in hair regrowth, especially on the crown, after using oral minoxidil and finasteride for four months and recently switched to dutasteride. The community responded positively, noting realistic progress and offering tips for consistent photo documentation. -
Discussion on Finasteride and life.
Chat Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices. -
What is everyone's stack and why?
Treatment People are using various treatments for hair loss, including dutasteride, finasteride, minoxidil (both oral and topical), RU58841, and ketoconazole shampoo. Some also use additional methods like microneedling, vitamins, and oils, with mixed results and personal preferences influencing their choices. -
3.5 months on fin/min progress
Progress Pictures A 22-year-old male has been using oral finasteride (1.2mg) and oral minoxidil (2.5mg) daily for 3.5 months, along with vitamin D, fish oil, iron, and biotin, and reports significant hair growth without side effects. The user plans to continue the treatment and is considering cutting hair to assess progress more accurately.
Effects of oxytocin receptor agonists on hair growth promotion
This study explores the use of oxytocin receptor (OXTR) agonists, LIT001 and WAY267464, as potential treatments for alopecia by promoting hair growth. These agonists were found to upregulate hair growth-related genes in dermal papilla cells and enhance hair shaft elongation in hair follicloids. The study addresses the limitations of oxytocin, such as its short half-life and low receptor specificity, which can cause side effects. LIT001 and WAY267464, with their lower molecular weights, may overcome these issues. Bioinformatic analysis suggests that low OXTR expression in dermal papilla cells is linked to hair loss, indicating OXTR as a promising therapeutic target. The study proposes that OXTR agonists could be effective alternatives to oxytocin, potentially offering additional benefits when combined with other treatments. Further research is needed to understand the mechanisms of these agonists and their effects on hair growth, as well as the potential of RNA-based therapies to enhance OXTR expression.
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New in research
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CGF Therapy: Bridging Androgenetic Alopecia Observations to Psoriasis Treatment via IL-17 Pathway
CGF therapy may effectively treat psoriasis by reducing inflammation.
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Synergistic Phytochemical and Pharmacological Actions of Hair Rise Microemulsion: A Novel Herbal Formulation for Androgenetic Alopecia and Hair Growth Stimulation
Hair RiseTM microemulsion effectively promotes hair growth and treats hair loss better than standard treatments.
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Platycladus Orientalis Leaf Extract Promotes Hair Growth Via Non-Receptor Tyrosine Kinase ACK1 Activation
Platycladus orientalis leaf extract helps hair grow by activating certain proteins.
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Evaluation of the Relationship Between Serum G Protein-Coupled Estrogen Receptors (GPER-1) Levels and the Severity and Duration of the Disease in Patients with Androgenetic Alopecia: A Case-Control Study
Higher GPER-1 levels are linked to more severe and shorter-duration androgenetic alopecia, suggesting GPER-1 as a potential treatment target.
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Red And Green LED Light Therapy: A Comparative Study In Androgenetic Alopecia
Red LED therapy is more effective than green LED for improving hair growth in androgenetic alopecia.
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Fusarium sp. Strain K-23 Alleviates Salt Stress in Arabidopsis thaliana Through Its Root Hair Growth-Promoting Effect
Fusarium sp. strain K-23 helps Arabidopsis plants grow better in salty soil by promoting root hair growth.
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Current Trends in Hair Care in Men
Proper hair care and suitable products are essential for men's scalp health and well-being.
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Vitamin D Deficiency in Non-Scarring and Scarring Alopecias: A Systematic Review and Meta-Analysis
Vitamin D deficiency is common in people with certain types of hair loss, like alopecia areata and female pattern hair loss.
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Baricitinib (Olumiant) for Severe Alopecia Areata Treatment Recommendations
Olumiant should be covered for severe alopecia areata if certain conditions are met.