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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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Fucoidan Treatment Reverses Hair Loss and Inhibits Inflammatory Responses in a Mouse Model of Androgenetic Alopecia
Research Fucoidan may help regrow hair and reduce inflammation in androgenetic alopecia. It is unclear if simply mixing fucoidan powder into a serum for application is effective. -
Mallia Aesthetics achieves key regulatory steps for novel sCD83-derived ingredient for hair growth
Research/Science Mallia Aesthetics has developed MAL-838, a hormone-free product derived from sCD83, which stimulates hair growth without disrupting the skin microbiome. sCD83 promotes hair growth by activating hair follicles and preventing cell death, offering a localized treatment without systemic side effects. -
I've been taking Finasteride daily for 20 yrs now.
Finasteride/Dutasteride Long-term finasteride users report that the drug may lose effectiveness over time, with some considering switching to dutasteride or adding minoxidil to their regimen. Many users suggest hair transplants or adjusting treatments to manage hair loss progression. -
26, 6 month progress on dut + min
Progress Pictures The user shared their 6-month progress using oral dutasteride and minoxidil for hair loss, noting improvements without significant side effects. They currently use 0.5mg oral dutasteride, 5mg oral minoxidil, 5% topical minoxidil, and ketoconazole shampoo twice a week. -
UPDATE - 3 month progress … true thoughts now
Is this regrowth? The user reported significant hair regrowth after using 1mg finasteride, 5% minoxidil twice daily, and dermarolling every 10 days. Others noted improvements and encouraged continued updates. -
1 year of .5mg oral dut, .3% topical fin and 6% topical min everyday
Finasteride/Dutasteride A 25-year-old is experiencing hair thinning despite using 0.5mg oral dutasteride, 0.3% topical finasteride, and 6% topical minoxidil daily for a year. They are considering increasing dutasteride dosage and exploring other treatments like microneedling and KX 826, while seeking further medical opinions on their condition.
New Featured Research
Vitamin D and its Analogs in Treatment of Mild to Moderate Alopecia Areata: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed the efficacy and safety of vitamin D3 and its analogs in treating mild to moderate alopecia areata (AA) across nine studies with 621 participants. The findings indicated a therapeutic efficacy of 53.75% for vitamin D3 treatments, with intralesional vitamin D3 being more effective than placebo in achieving significant hair regrowth. Topical vitamin D3 analogs also reduced the Severity of Alopecia Tool (SALT) score, though not significantly compared to placebo. Combining vitamin D3 analogs with treatments like corticosteroids or narrowband UVB enhanced therapeutic effects. The studies reported mild adverse effects and low recurrence rates, suggesting vitamin D3 as a stable treatment option, though more effective when used as an adjuvant therapy rather than alone. The study calls for standardized protocols to improve future research consistency.
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New in research
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Comparison of the Efficacy of Topical Methotrexate 1% Gel Versus Topical Betamethasone Dipropionate 0.05% Lotion in the Treatment of Localized Scalp Alopecia Areata in a Tertiary Care Institute of Central India: A Randomized Control Trial
Both treatments work equally well for hair regrowth, but the lotion has fewer side effects.
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Hemp Seed-Derived Exosomes Protect Against Dihydrotestosterone-Induced Chicken Feather Growth Inhibition
Hemp seed-derived exosomes help restore feather growth in chickens affected by DHT.
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Discontinuation and Restart of Janus Kinase Inhibitors Due to Pregnancy in Alopecia Areata: A Case Series
Stopping and restarting JAK inhibitors during pregnancy in women with alopecia areata leads to hair loss and regrowth, with most pregnancies resulting in healthy babies.
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Composite Hydrogel Dressing with Drug-Release Capability and Enhanced Mechanical Performance
The hydrogel dressing improves wound healing, offers long-lasting antibacterial effects, and enhances patient comfort.
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Evaluating Current and Emerging JAK Inhibitors for Alopecia Areata: A Narrative Review
JAK inhibitors show promise for treating alopecia areata but have serious side effects.
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Technological Advances in Anti-Hair Loss and Hair Regrowth Cosmeceuticals: Mechanistic Breakthroughs and Industrial Prospects Driven by Multidisciplinary Collaborative Innovation
Collaboration and innovation are key to developing effective, safe hair loss treatments.
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Therapeutic Effects of Topical Mycophenolate Mofetil on Hydroquinone-Induced Depigmentation in Guinea Pigs and Mice
Mycophenolate mofetil may safely help restore skin color in depigmentation conditions.
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Does Hair Loss Impact Mood, Self-Esteem, Body Image, and Quality of Life in Patients with Androgenetic Alopecia?
Hair loss can affect mood, self-esteem, body image, and quality of life.
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Machine Learning-Driven Optimization of Therapeutic Substance Composition for High-Hardness, Fast-Dissolving Microneedles for Androgenetic Alopecia Treatment
Machine learning optimized microneedles for hair loss treatment showed better hair regrowth than minoxidil without safety risks.