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New in community
- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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45M: Suggestions? Keto + LLLT working, can’t do Min, Fin, or Dut
General A 45-year-old male successfully slowed hair loss using Nizoral and low-level laser therapy (LLLT) but cannot use Minoxidil, finasteride, or dutasteride for medical reasons. He seeks suggestions for hair regrowth options. -
18M 4 months on fin. Is my medication working?
Journals / Progress Pictures An 18-year-old is using 0.1% topical finasteride and 1.25 mg oral minoxidil daily for hair loss. After four months, they experienced initial thinning but some regrowth, and are considering switching to dutasteride due to aggressive hair loss. -
Shave it or treat it need advise on mpb genetic
General A 31-year-old experiencing rapid hair loss is considering whether to shave their head or use treatments. They were prescribed B12, topical finasteride 0.1%, and minoxidil 10% but are unsure about the correct dosage and potential side effects. -
Should I stop minox. or find alternatives ? Or keep pushing through?
General The user experienced side effects like heart palpitations, chest tightness, and fatigue from using 5% minoxidil foam once daily. They are considering switching to a 2% concentration due to lingering symptoms like lightheadedness and brain fog. -
Advice on Disposing or Donating Unused Minoxidil Tablets
General Unused Minoxidil tablets should be disposed of at a pharmacy with take-back services or according to packaging instructions. It's not recommended to give them to others due to legal and safety concerns. -
Jan 30 Update (4 months and amazing huge progress) fin + min + 3 PRP sessions
Progress Pictures A user shared impressive hair regrowth results after 4 months using topical minoxidil, oral finasteride, and 3 PRP sessions. They plan to continue with these treatments and add dermastamping.
New Featured Research
Role of ASLNC168501 in regulating hair follicle stem cell activity via the AR/miR-128-3p/IGF-1 pathway
This study identifies the AR/miR-128-3p/IGF-1 pathway as crucial in the dysfunction of hair follicle stem cells (HFSCs) in androgenetic alopecia (AGA). It finds that reduced IGF-1 expression impairs HFSCs activity, with AR activating miR-128-3p to suppress IGF-1. ASLNC168501, acting as a competing endogenous RNA, sequesters miR-128-3p, restoring IGF-1 levels. Overexpressing ASLNC168501 in dermal papilla cells enhances HFSCs' self-renewal and differentiation, reversing hair follicle atrophy in AGA mice, suggesting ASLNC168501 as a promising therapeutic target for AGA treatment.
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New in research
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Protective Effects of Wheat Sprouts Extract Against Acrylamide-Induced Skin Toxicity: Modulation of Oxidative Stress, Apoptosis, and Histomorphometric Alterations in Rats
Wheat sprout extract can protect skin from toxin damage.
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Assessing Dihydrotestosterone-Induced Skin Alterations in C57BL/6 Mice: Implications for Androgenetic Alopecia Through High-Resolution Ultrasound Imaging
DHT causes thicker and less elastic skin, linked to hair loss.
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What Are the Clinical Guidelines for Diagnosing and Managing Androgenic Alopecia in Adults in General Practice?
Androgenic alopecia is diagnosed by clinical evaluation and managed with treatments to stop hair loss and encourage regrowth.
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Comparative Effectiveness of Regenerative Biologics in Aesthetic Dermatology: A Systematic Review with Quantitative Synthesis Evaluating Exosomes, PRP, and Stem-Cell-Derived Therapies on Skin and Hair
Exosomes and stem-cell therapies slightly outperform PRP in improving hair and skin, but more research is needed.
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What Are the Clinical Guidelines for Diagnosing and Managing Androgenic Alopecia in Adults in General Practice?
Androgenic alopecia is diagnosed by clinical evaluation and managed with treatments to stop hair loss and encourage regrowth.
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Comparative Effectiveness of Regenerative Biologics in Aesthetic Dermatology: A Systematic Review with Quantitative Synthesis Evaluating Exosomes, PRP, and Stem-Cell-Derived Therapies on Skin and Hair
Exosomes and stem-cell therapies slightly outperform PRP in improving hair and skin, but more research is needed.
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A Critical Review: Recent Advances in Ethosomal Gel for Transdermal Drug Delivery Systems
Ethosomal gels improve drug delivery through the skin, enhancing treatment effectiveness.
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A Critical Review: Recent Advances in Ethosomal Gel for Transdermal Drug Delivery Systems
Ethosomal gels improve drug delivery through the skin, enhancing treatment effectiveness.
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Is There an Association Between 25(OH)D Serum Levels and Vitamin D Status with the Severity of Androgenetic Alopecia in Men?
Lower vitamin D levels are linked to more severe hair loss in men.