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- Featured Community Post
Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
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Scalp itching on fin for 2 years need hellppp
General The user has been experiencing severe scalp itching and red spots after using finasteride for two years, suspecting possible allergies or a fungal infection. Despite trying ketoconazole shampoo and stopping saw palmetto supplements, the symptoms persist, leading to increased hair loss. -
How can ketoconazole shampoo block androgen receptor if it's just washed off?
Ketoconazole Ketoconazole shampoo is primarily used to reduce scalp fungus and inflammation, not to block DHT or androgen receptors. It may help with seborrheic dermatitis and improve scalp health, but its effects on hair loss are minimal compared to treatments like finasteride. -
Started minoxidil but very afraid and reluctant to start finasteride
General A 22-year-old is using minoxidil for hair loss but is hesitant to start finasteride due to mixed advice and fear of side effects. They seek guidance on whether to begin finasteride despite concerns about potential permanent side effects. -
Switch to dut or increase to 1mg fin?
Treatments The user has been using 0.5mg finasteride daily for two years without side effects but is considering switching to dutasteride or increasing finasteride to 1mg for better results. They are unsure whether to proceed with dutasteride or increase the finasteride dosage. -
Large Dandruff Flakes Causing Hair Loss
General A 23-year-old male is experiencing large dandruff flakes causing hair loss, despite using anti-dandruff shampoo. He seeks advice on resolving the issue, noting a family history of baldness. -
Weird hair loss pattern, localized on the front of my scalp, what gives?
General The user is experiencing significant hair thinning on the front scalp while taking oral finasteride and minoxidil. They are unsure if it's androgenetic alopecia or related to seborrheic dermatitis.
New Featured Research
Complete Clinical and Trichoscopic Remission of Refractory Patch Alopecia Areata with a Multi-Modal Microneedling and Vitamin D3 Protocol: A Case Report
This case report describes a 44-year-old female with refractory patch alopecia areata who achieved complete clinical and trichoscopic remission using a multi-modal treatment protocol. The protocol included systemic vitamin D3 supplementation (5,000 IU/day), 10 sessions of microneedling, and topical application of high-dose vitamin D3. Significant hair regrowth was observed by week 12, with complete regrowth by week 20. The patient's vitamin D levels improved from 18.2 ng/mL to 41.5 ng/mL. While the exact contribution of each treatment component is unclear, the case suggests that a combined approach may be effective for refractory patch alopecia areata and warrants further study.
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New in research
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Phenytoin or Spironolactone Intervention Counteracts 5-Fluorouracil-Induced Alopecia in Rats by Suppressing Oxidative Stress and Inflammation While Promoting Collagen Synthesis
Phenytoin and spironolactone help prevent hair loss from chemotherapy by reducing stress and inflammation.
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Using the Mechanisms of Action Involved in the Pathogenesis of Androgenetic Alopecia to Treat Hair Loss
Combining different drugs can improve hair loss treatment.
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Polycystic Ovary Syndrome: A Complex Interplay of Hormones and Metabolism
PCOS involves hormonal and metabolic issues, increasing risks for diabetes and heart disease, and requires lifestyle changes and medication for management.
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Quercetin Promotes Production of Secondary Hair Follicle Stem Cells in Cashmere Goat: A Mechanistic Study
Quercetin boosts hair follicle stem cell growth and survival in cashmere goats.
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Effects of GLP-1 Receptor Agonists on Hair Loss and Regrowth: A Systematic Review
GLP-1 receptor agonists may cause hair loss, but regrowth is rare.
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Dermatological Alterations Induced by Gynecological Hormonal Imbalances: Acne, Hirsutism, and Alopecia
Hormonal imbalances can cause acne, excess hair growth, and hair loss in women, needing combined medical and emotional care.
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Amitriptyline-Induced Telogen Effluvium in a Patient with Cervical Disc Prolapse: A Case Report
Amitriptyline can cause temporary hair loss, which stops after discontinuing the drug.
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Psoriasis and Alopecia: Unveiling the Links
Psoriasis patients are more likely to develop alopecia areata due to complex autoimmune interactions.
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Hyperandrogenism Insulin Resistance-Acanthosis Nigricans Syndrome in a Female Adolescent with Migraine: A Case Report
Early diagnosis and treatment of endocrine disorders like HAIR-AN syndrome can improve outcomes in adolescents.