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GlossaryAbiraterone (Zytiga)

inhibits androgen production to treat prostate cancer

Abiraterone, also known as Zytiga, is a medication used primarily to treat prostate cancer. It works by inhibiting an enzyme called CYP17, which is involved in the production of androgens (male hormones) that can fuel the growth of prostate cancer cells. By reducing androgen levels, abiraterone helps to slow the progression of the disease.

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research Steroidal 5α-Reductase and 17α-Hydroxylase/17,20-Lyase (CYP17) Inhibitors Useful in the Treatment of Prostatic Diseases

51 citations, May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology”

Certain drugs that block specific enzymes can help treat prostate diseases.

research Recent Discoveries and Developments of Androgen Receptor-Based Therapy for Prostate Cancer

17 citations, January 2015 in “MedChemComm”

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases

11 citations, February 2016 in “Current Medicinal Chemistry”

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

research Triple Hormonal Blockade (ADT3): A Patient’s Perspective

January 2019 in “Oncogen”

Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.

research Steroid Hormones of Reproduction and Sexual Development

January 2017 in “Elsevier eBooks”

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

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community Why you should use 0.5mg Dut instead of 1mg Fin

in Finasteride/Dutasteride 45 upvotes 2 years ago

The comparison of 0.5mg dutasteride and 1mg finasteride for treating hair loss in men with androgenetic alopecia, with discussion of which is more effective and has fewer side effects.