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Glossary Zinc Transporter

protein that moves zinc ions across cell membranes

A zinc transporter is a type of protein that helps move zinc ions in and out of cells or organelles within cells. These transporters are crucial for maintaining proper zinc levels, which are essential for various biological functions, including immune response, enzyme activity, and hair growth. Inadequate zinc transport can lead to deficiencies or toxicities, impacting overall health and conditions like alopecia.

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Research

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research Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10–p63 axis in epithelial homeostasis

59 citations , October 2017 in “Proceedings of the National Academy of Sciences”

This study found that the zinc transporter ZIP10 is crucial for epidermal development, as it influences the activity of p63, promoting epidermal morphogenesis.

research The Role of the Slc39a Family of Zinc Transporters in Zinc Homeostasis in Skin

19 citations , February 2018 in “Nutrients”

This review discusses the relationship between zinc deficiency and skin disorders, emphasizing zinc transporters' roles, but it reports no new clinical results; the authors highlight potential benefits of regulating zinc levels via transporters.

research Zinc and Zinc Transporters in Dermatology

4 citations , December 2022 in “International Journal of Molecular Sciences”

This review discusses the role of zinc and its transporters in skin health and disorders, providing an overview without presenting new clinical results.

Zinc Transporter ZIP13 G289R Variant From Spondylocheirodysplastic Ehlers-Danlos Syndrome Is Associated With Abnormal Hair Quality

research Zinc transporter ZIP13 G289R variant from Spondylocheirodysplastic Ehlers-Danlos syndrome (SCD-EDS) is associated with abnormal hair quality

February 2025 in “Journal of Investigative Dermatology”

The ZIP13 variant is linked to abnormal hair quality.

research The ZIP7 Gene (Slc39a7) Encodes a Zinc Transporter Involved in Zinc Homeostasis of the Golgi Apparatus

195 citations , February 2005 in “Journal of biological chemistry/The Journal of biological chemistry”

This study shows that ZIP7 is a functional zinc transporter in mammalian cells, facilitating the movement of zinc from the Golgi apparatus to the cytoplasm.

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Community Join

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community My hair transformation oral fin+min topical min and HT

37 upvotes 1 year ago

The user is 6 months post-hair transplant and uses finasteride, oral and topical minoxidil, along with supplements like omega-3, vitamin D3, and zinc. They are experiencing significant shedding and seek advice on whether the medications are effective and if the shedding will settle.

community My hair transformation Journey DONT GIVE UP

in Transplants 64 upvotes 4 months ago

A 30-year-old male with androgenic alopecia started using topical Minoxidil in 2018, Finasteride in 2020, and switched to oral Minoxidil and Dutasteride after Finasteride stopped working. He underwent hair transplants in 2022 and 2025, showing significant improvement in recent photos.

community 3 months transformation (Min+Fin+Derma Roller)

in Progress Pictures 15 upvotes 1 year ago

The conversation is about a user's 3-month hair loss treatment using topical minoxidil, oral finasteride, a derma roller, ketoconazole shampoo, rosemary oil, and vitamin D supplements, alongside weight loss. Users discuss shedding, vitamin D benefits, and reducing sugar intake.

community Has anyone used zinc as a treatment?

24 upvotes 1 year ago

Zinc is not effective for hair loss unless there's a deficiency. Finasteride and minoxidil are recommended treatments.

community My hairloss started at 17 - Transformation. Bald to full head of hair.

1 year ago

The user shared their journey from hair loss at 17 to a full head of hair using topical finasteride, Saw Palmetto, a natural serum with stem cells and rosemary oil, dermarolling, and a specialized shampoo. They experienced side effects with Dutasteride and found success with their current routine without side effects.

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Learn

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learn zinc PCA

Why is zinc important for preventing hair loss and supporting hair follicle function? Zinc is crucial for hair follicle health, supporting growth and repair processes.
Should zinc be taken orally or applied topically for better results in hair growth? Oral zinc supplementation is generally more effective for promoting hair growth than topical application.
Can a zinc deficiency directly cause hair thinning or increased shedding? Studies link low serum zinc to diffuse shedding and alopecia areata, and severe deficiency states cause hair loss that reverses when zinc is replaced. The evidence is mostly observational, the one supplementation study was small and uncontrolled, and zinc is not a treatment for pattern hair loss.
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