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research A novel missense mutation (C622G) in the zinc‐finger domain of the human hairless gene associated with congenital atrichia with papular lesions

47 citations , April 2000 in “Experimental Dermatology”

This study identified a novel missense mutation in the hairless gene in a Polish family, which may contribute to congenital atrichia with papular lesions by affecting the gene's function.

research Dynamic expression of the zinc-finger transcription factor Trps1 during hair follicle morphogenesis and cycling

46 citations , November 2007 in “Gene Expression Patterns”

This study observed that Trps1 gene expression in mice is precisely regulated in skin development, particularly during hair follicle morphogenesis, with distinct localization patterns in different cell types.

research A Missense Mutation in the Zinc-Finger Domain of the Human Hairless Gene Underlies Congenital Atrichia in a Family of Irish Travellers

83 citations , October 1998 in “The American Journal of Human Genetics”

A specific gene mutation causes complete hair loss in an Irish Traveller family.

research A Homozygous Nonsense Mutation in the Zinc-Finger Domain of the Human Hairless Gene Underlies Congenital Atrichia

37 citations , August 1999 in “Journal of Investigative Dermatology”

This study identified a nonsense mutation in the zinc-finger domain of the hairless gene associated with congenital atrichia in a Japanese family, indicating a potential genetic cause for this rare form of alopecia.

research Arabidopsis ZINC FINGER PROTEIN1 Acts Downstream of GL2 to Repress Root Hair Initiation and Elongation by Directly Suppressing bHLH Genes

101 citations , November 2019 in “The Plant Cell”

This study found that the zinc finger protein AtZP1 inhibits root hair initiation and elongation in Arabidopsis by suppressing key transcription factors involved in root hair development.

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community Why i think that zinc/lifting weights/caffeine is the catalyst of hair loss

in Research/Science 1 year ago

The conversation discusses the belief that zinc, caffeine, and weightlifting may contribute to hair loss by increasing DHT levels. The original poster plans to reduce zinc and caffeine intake and stop weightlifting to see if it improves their hair condition.

community Exactly One Year On Finestride Today...

4 upvotes 4 years ago

The user has been using finasteride, minoxidil, ketoconazole shampoo, and a dermaroller for hair loss, noticing slowed hair loss but no regrowth. They recently added vitamins, zinc, and rosemary oil, seeking further advice on effective treatments.

community finasteride not working help !

in Finasteride/Dutasteride 2 years ago

A user is experiencing worsening hair loss despite using finasteride, PRP treatments, and supplements like vitamin D, biotin, zinc, and iron. They are seeking advice on whether to continue with finasteride, increase the dosage, or try additional PRP sessions.

community Accepting that I got side effects from Fin. Where do I go from here?

5 upvotes 9 years ago

The conversation discusses the side effects of finasteride, including sexual dysfunction, and the dilemma of whether to continue its use for hair loss. The original poster considers tapering off the drug and using supplements like zinc, while also using minoxidil for hair maintenance.

community So what other supplements should you take alongside finasteride.

4 upvotes 1 year ago

The conversation discusses using finasteride for hair loss and considers additional supplements like vitamin D3, melatonin, zinc, biotin, and minoxidil. There is debate over zinc's effectiveness, with some suggesting it may not be beneficial for hair loss.

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learn zinc PCA

Why is zinc important for preventing hair loss and supporting hair follicle function? Zinc is crucial for hair follicle health, supporting growth and repair processes.
Should zinc be taken orally or applied topically for better results in hair growth? Oral zinc supplementation is generally more effective for promoting hair growth than topical application.
Can a zinc deficiency directly cause hair thinning or increased shedding? Studies link low serum zinc to diffuse shedding and alopecia areata, and severe deficiency states cause hair loss that reverses when zinc is replaced. The evidence is mostly observational, the one supplementation study was small and uncontrolled, and zinc is not a treatment for pattern hair loss.
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