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GlossaryX-ray diffraction (X-ray crystallography)

technique to determine atomic structure of crystals using X-rays

X-ray diffraction (XRD) is a technique used to study the atomic structure of crystalline materials. By directing X-rays at a crystal and analyzing the pattern of the rays that are scattered, scientists can determine the arrangement of atoms within the crystal. This method is crucial for understanding the molecular structure of various substances, including biological molecules like proteins and DNA.

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Hyaluronic Acid Microneedles Enhance Transdermal Delivery of Minoxidil Derivatives with 1,2,4-Oxadiazole-5-One Unit for Effective Hair Regeneration: Insights from X-Ray Crystallography and Animal Models

research Hyaluronic Acid Microneedles Enhance Transdermal Delivery of Minoxidil Derivatives with 1,2,4-Oxadiazole-5-One Unit for Effective Hair Regeneration: Insights from X-Ray Crystallography and Animal Models

October 2025 in “Journal of Molecular Structure”

Hyaluronic acid microneedles help deliver minoxidil derivatives effectively for hair regrowth.

research Structural Characterization of Polymorphs and Molecular Complexes of Finasteride

17 citations , January 1999 in “Journal of Molecular Structure”

Finasteride's molecular and crystal structures help develop new drug formulations.

research Aromatic C-Nitrosation of a Bioactive Molecule: Nitrosation of Minoxidil

8 citations , January 2011 in “Organic and Biomolecular Chemistry”

Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.

Minoxidil/Salicylic Acid Hydrogel Formulated for Alopecia Treatment: Supramolecular Interactions Modulate Physicochemical Properties and Biological Activities

research Minoxidil/Salicylic Acid Hydrogel Formulated for Alopecia Treatment: Supramolecular Interactions Modulate Physicochemical Properties and Biological Activities

February 2024 in “Journal of Molecular Structure”

The new minoxidil and salicylic acid hydrogel improves alopecia treatment.

research Structural and Functional Studies of L-PGDS and SMPDL3A Enzymes in Lipid Signaling Family

October 2019

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

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community Say this new supposed miracle drug “PP405” does actually cure baldness, how will that affect people with hair transplants?

in Chat 204 upvotes 3 months ago

PP405 may reactivate dormant hair follicles but won't replace hair transplants or resurrect dead follicles. Its effectiveness, cost, and impact compared to treatments like minoxidil and finasteride are uncertain.

community I bought 72 packages of Dutasteride

in Chat 113 upvotes 1 year ago

A user traveled to Turkey to buy 72 packages of Dutasteride for a year-long supply and successfully brought them back home. They plan to use 2.5mg of Dutasteride daily along with RU58841 for hair loss.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Anyone use hair fiber products like Toppik?

in Question 21 upvotes 6 years ago

User phoenixblue asked about hair fiber products like Toppik and if they cause hair loss by clogging pores. Replies suggested that Toppik is safe, but effectiveness varies; some users experienced no hair loss, while others had issues with color or sweating.

community Oral Minoxidil- Be Careful!!!!!

in Minoxidil 417 upvotes 3 months ago

Oral minoxidil can cause severe side effects, including heart issues, even at low doses. Users suggest starting with a lower dose or using topical treatments to minimize risks.

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