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research Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia

195 citations , June 2005 in “American Journal of Human Genetics”

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

research Disorders of the Scalp and Hair

January 2018

Different scalp and hair disorders are more common in certain ethnic groups, with the most common being androgenetic alopecia, which is treated with medications like minoxidil and finasteride.

research Male Androgenetic Alopecia

100 citations , April 2010 in “Expert Opinion on Pharmacotherapy”

Hair loss in men treated best with early medication or transplant, new treatments researched.

research Visualizing Androgen Receptor Activity in Male and Female Mice

89 citations , August 2013 in “PloS one”

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

research Chromosomal Localization of Mouse Hair Keratin Genes

21 citations , December 1991 in “Annals of the New York Academy of Sciences”

Most mouse hair keratin genes are on chromosomes 11 and 15.

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community Why do we have head hair in first place if we evolved to start losing it in some cases as soon as puberty hits

in Chat 140 upvotes 2 months ago

Hair loss is influenced by genetics and sensitivity to hormones like DHT. Treatments like Minoxidil and finasteride are commonly used, and baldness persists as it doesn't affect reproductive success.

community Hair loss and ethnicity - Caucasian men the most likely to experience hair loss

in Chat 17 upvotes 3 years ago

The conversation discusses how Caucasian men are more likely to experience hair loss due to genetic predisposition, with factors like the androgen receptor on the X chromosome playing a significant role. The user also expresses confusion about the evolutionary reasons for hair loss, especially in colder climates where it would seem beneficial to retain hair for warmth.

community This sub in a nutshell when it comes to medicine. Oral Minoxidil isn’t that bad

in Chat 446 upvotes 2 years ago

The post and conversation are about the use of oral Minoxidil (Min), Finasteride (Fin), and RU58841 for hair loss treatment, with mixed opinions on their safety and effectiveness.

community Chromosome 20’s balding effects and why fin likely isn’t working for some.

in Treatment 96 upvotes 2 months ago

Finasteride is effective for DHT/AR-driven hair loss but not for chromosome 20-driven cases, where treatments like minoxidil, prostaglandin analogs, and low-level laser therapy may be more beneficial. Genetic testing can help determine the underlying cause of hair loss to tailor treatment effectively.

community I want to sacrifice my hair in the name of science

in Chat 12 upvotes 2 years ago

The conversation discusses various theories of hair loss, including DHT sensitivity and genetic factors, with the user willing to use themselves for research due to having a hair loss gene but different hair loss patterns compared to their brothers. Specific treatments were not mentioned in the provided text.

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