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research An unusual presentation of X-linked adrenoleukodystrophy

2 citations , November 2015 in “Endocrinology, Diabetes & Metabolism Case Reports”

This case report describes a 57-year-old man's late diagnosis of X-linked adrenoleukodystrophy, highlighting the need to consider this condition in patients with non-autoimmune primary adrenal insufficiency and neurological issues.

research An X-Linked Gene Involved in Androgenetic Alopecia: A Lesson to Be Learned from Adrenoleukodystrophy

24 citations , January 2000 in “Dermatology”

This study found that men with adrenomyeloneuropathy often experience diffuse hair loss and severe male-pattern baldness, potentially due to the X-linked ALD mutation's role in androgenetic alopecia's genetic spectrum.

research Diffuse hair loss in Addison disease: A reason for X-linked adrenoleukodystrophy screening

3 citations , April 2012 in “Journal of the American Academy of Dermatology”

Men with Addison disease should be screened for X-linked adrenoleukodystrophy if they have hair loss.

research Fructose-1,6-bisphosphate aldolase A levels decrease in hair keratinocytes during androgenetic alopecia

2 citations , January 2013 in “International Journal of Dermatology”

ALDOA levels drop in hair cells during hair loss.

research Oral intake of anti-hangover substance increases aldehyde dehydrogenase activity: New preventive and therapeutic potentials for oxidative neuronal injury?

1 citations , December 2015 in “Parkinsonism & Related Disorders”

The anti-hangover product may boost enzyme activity to help prevent brain damage.

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community A New Therapeutic Channel to Come Soon: Hair Follicle Sugar Metabolism and Aldose Reductase

131 upvotes 5 years ago

Hair loss therapies focusing on hair follicle sugar metabolism and aldose reductase. Potential treatments include magnesium supplements, avoiding high glycemic index foods, and antioxidants.

community [19 F] Scared of balding. What can I do?

5 upvotes 13 years ago

A 19-year-old woman is concerned about hair thinning and seeks advice. Recommendations include using minoxidil, Nizoral shampoo, spironolactone, and possibly birth control, along with consulting a doctor for a proper diagnosis and treatment plan.

community Trying to understand finasteride side effects and post finasteride syndrome

70 upvotes 5 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community The Biggest Concern That I Have For Oral Minoxidil: Cardiac Hypertrophy

26 upvotes 3 years ago

Oral minoxidil can cause serious heart issues like cardiac hypertrophy and arrhythmias, prompting some users to reduce dosage or switch to topical treatments. Despite significant hair regrowth, side effects such as shortness of breath and chest pains are common concerns.

community Oral Minoxidil and the "Facial Bloating" - what the research actually says

43 upvotes 4 months ago

Oral minoxidil can cause rare facial bloating, especially at higher doses and in women. Reducing sodium intake, drinking more water, and adjusting the dose can help manage side effects.

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