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    Glossary Wounding

    deliberate or accidental damage to skin or tissues

    Wounding refers to the deliberate or accidental damage to the skin or underlying tissues. In the context of hair and alopecia, wounding can stimulate hair growth by triggering the body's natural healing processes, which can activate dormant hair follicles. This concept is utilized in treatments like microneedling, where tiny needles create controlled micro-injuries to promote hair regrowth.

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    1. Wound Healing: A Cellular Perspective Physiological Reviews · 2018 · 1160 citations
    2. Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties Nature cell biology · 2017 · 143 citations
    3. Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes ˜The œAmerican journal of pathology · 2005 · 81 citations
    4. Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing Science Advances · 2021 · 66 citations
    5. Epigenetic control of skin and hair regeneration after wounding Experimental Dermatology · 2014 · 36 citations
    6. Pigmentation of regenerated hairs after wounding Journal of Dermatological Science · 2016 · 16 citations
    7. Role of vitamin D and calcium signaling in epidermal wound healing Journal of endocrinological investigation · 2022 · 15 citations
    8. β-Catenin–Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding [RETRACTED] Plastic and Reconstructive Surgery · 2018 · 13 citations
    9. Salicylate induces epithelial actin reorganization via activation of the AMP-activated protein kinase and promotes wound healing and contraction in mice Scientific Reports · 2024 · 8 citations
    10. Wound healing mechanism in Mongolian gerbil skin Histochemistry and Cell Biology · 2018 · 6 citations
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    Community 6

    1. The use of peptides to enhance hair growth from wounding Reddit · 24 May 2017
    2. Could PP405 restore extracted hair follicles after transplant? Reddit · 23 Jun 2025
    3. How does it feel to microneedle at 0.3mm? Reddit · 14 Apr 2024
    4. Vertoporfin research update by Dr Bloxham Reddit · 13 Nov 2023
    5. Another molecular pathway to promote scarless healing and regenerate hair follicles Reddit · 8 Jan 2026
    6. Losing Hope, Not Sure if I should keep fighting Reddit · 31 Jan 2021

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