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research Macrophages in Skin Wounds: Functions and Therapeutic Potential

56 citations , November 2022 in “Biomolecules”

This review explores the role of macrophage subsets in adult cutaneous wound healing and emphasizes their potential for therapeutic targeting, but reports no new experimental results.

research M2 macrophages promote wound-induced hair neogenesis

27 citations , May 2018 in “Journal of Dermatological Science”

This study suggests that M2 macrophages play a key role in promoting wound-induced hair neogenesis in mice by producing growth factors like Igf1 and Fgf2.

ADM Scaffolds Generate a Pro-Regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1

research ADM Scaffolds Generate a Pro-regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1

17 citations , June 2018 in “Frontiers in Physiology”

This study found that acellular dermal matrix scaffolds may facilitate full-thickness skin wound healing by promoting a pro-regenerative immune response through M2 macrophage polarization via the Lamtor1 pathway.

Type 2-Mediated Oxidative Reprogramming Promotes Macrophage Transition into Repair Mode for Wound Healing

research 1497 Type 2-mediated oxidative reprogramming promotes the transition of macrophages into repair mode and is required for wound healing

April 2023 in “Journal of Investigative Dermatology”

This study identified a new role for IL-4Ra-induced oxidative metabolism in wound macrophages, essential for balancing inflammatory response and promoting pro-fibrotic repair, suggesting a target for fibrosis prevention.

research 741 Identification of a specific subset of monocytes/macrophages that coordinates skin wound healing

April 2016 in “Journal of Investigative Dermatology”

This study found that the CD301b-expressing subpopulation of macrophages plays a crucial role in promoting reparative processes during the mid-stage of skin wound healing in a mouse model.

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community The Worst Hair Loss Condition You (MAY) have: LPP

48 upvotes 2 years ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Would this DUT work? Or just BS

24 upvotes 4 weeks ago

The conversation discusses the effectiveness and side effects of using Dutasteride, particularly at higher doses like 2.5mg, for hair loss treatment. Concerns are raised about potential side effects, long-term safety, and the difference between topical and oral applications.