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This review discusses the roles of mesenchymal stem cells in wound healing, particularly their interactions with immune cells, and highlights the potential and current limitations of MSC-based therapies for tissue regeneration.

In this double-blind, placebo-controlled study, researchers found that low-level laser therapy significantly improved the healing rate and reduced the area of pressure ulcers in patients compared to placebo, suggesting its effectiveness in managing ulcers resistant to conventional treatments.

This study observed that mature neutrophils and their extracellular traps inhibit wound-induced hair follicle neogenesis in mice, despite being stimulated by pro-regenerative cues.

In this study, researchers found that intestine-derived human alpha defensin 5 enhances wound healing, reduces bacterial load, and promotes hair growth in murine burn wound beds by increasing LGR stem cell migration.

In this study using mice and human keratinocyte cells, researchers found that activating PKM2-mediated glycolysis and Wnt/β-catenin signaling, particularly via combined treatments, significantly accelerated wound healing and induced angiogenesis in wound beds.