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research MiR-27a Targeting PIK3R3 Regulates the Proliferation and Apoptosis of Sheep Hair Follicle Stem Cells

1 citations, December 2022 in “Animals”

Blocking miR-27a increases sheep hair follicle stem cell growth and decreases cell death, which could help improve wool quality and treat hair loss.

research Epigenetic Mechanism of Gtl2-miRNAs Causes the Primitive Sheep Characteristics Found in Purebred Merino Sheep

October 2023 in “Cell & bioscience”

A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.

Induction of Hair Follicle Dermal Papilla Cell Properties in Human Induced Pluripotent Stem Cell-Derived Multipotent LNGFR(+)THY-1(+) Mesenchymal Cells

research Induction of Hair Follicle Dermal Papilla Cell Properties in Human Induced Pluripotent Stem Cell-Derived Multipotent LNGFR(+)THY-1(+) Mesenchymal Cells

42 citations, February 2017 in “Scientific Reports”

Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.

research Single-Cell Transcriptomics Reveals the Molecular Anatomy of Sheep Hair Follicle Heterogeneity and Wool Curvature

10 citations, December 2021 in “Frontiers in cell and developmental biology”

The research identified genes that explain why some sheep have curly wool and others have straight wool.

research The Germinative Epithelium of Sheep Vibrissae and Wool Follicles Has Extensive Proliferative Potential but Is Dependent on the Dermal Papilla

1 citations, January 2012 in “International journal of trichology”

Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.

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community Is there any point to microneedling if you're on oral minoxidil?

in Microneedling 45 upvotes 1 year ago

Microneedling's effectiveness for hair regrowth is debated, with mixed results from studies. Some believe it helps with blood flow and scalp health, while others see it as largely ineffective.

community 1.5 years fin plus almost 3 years min, I think I’ve definitely made progress but I’m still not where I want to be, advice?

in Progress Pictures 130 upvotes 10 months ago

The user has been using finasteride for 1.5 years and minoxidil for almost 3 years for hair loss, and has seen some maintenance of hair but not significant regrowth. Suggestions from others include switching to dutasteride, trying oral minoxidil, and considering microneedling or hair fibers for better appearance.

community Ru58841 ruined my life. Here’s why.

in Product 127 upvotes 2 years ago

User experienced shortness of breath, high blood pressure, red eyes, and eye floaters after using RU58841 for hair loss. They warn others to avoid RU58841 and stick to finasteride, minoxidil, and dutasteride.

community DIY treatment... Shedding completely stopped after 1.5 yrs

in Treatment 246 upvotes 2 years ago

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.

community If people technically have hair follicles all over their body with baby hairs, why is regrowing hair so difficult to do?

in Chat 8 upvotes 4 months ago

Hair loss treatments are difficult because hair follicles react differently to hormones and have varying growth cycles. Treatments mentioned include Minoxidil, finasteride, and RU58841.

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