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GlossaryWnt3a (Wnt-3a protein)

protein crucial for hair follicle development and regeneration

Wnt3a is a protein that plays a crucial role in cell signaling pathways, particularly in the regulation of cell growth, development, and differentiation. In the context of hair biology, Wnt3a is important for hair follicle development and regeneration, as it helps activate the pathways that promote hair growth and prevent hair loss.

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research Liposomal Packaging Generates Wnt Protein with In Vivo Biological Activity

75 citations, August 2008 in “PLOS ONE”

Wnt3a protein, when packed in liposomal vesicles, can stimulate hair growth and could potentially treat conditions like hair loss.

research Isolation and Characterization of Recombinant Murine Wnt3a

3 citations, November 2014 in “Protein Expression and Purification”

Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.

research Sustained Release of Dermal Papilla-Derived Extracellular Vesicles from Injectable Microgel Promotes Hair Growth

46 citations, January 2020 in “Theranostics”

Injecting a special gel with human protein particles can help hair grow.

Pre-Aggregation of Scalp Progenitor Dermal and Epidermal Stem Cells Activates the WNT Pathway and Promotes Hair Follicle Formation In Vitro and In Vivo Systems

research Pre-Aggregation of Scalp Progenitor Dermal and Epidermal Stem Cells Activates the WNT Pathway and Promotes Hair Follicle Formation In Vitro and In Vivo Systems

17 citations, December 2019 in “Stem Cell Research & Therapy”

Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.

research Hair Growth-Promoting Effect of Human Dermal Stem/Progenitor Cell-Derived Conditioned Medium

9 citations, August 2015 in “Tissue Engineering and Regenerative Medicine”

Human skin cell byproducts can potentially be used to treat hair loss and promote hair growth.

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community Better Than Minoxidil? Topical Sodium Valproate

in Research/Science 53 upvotes 2 months ago

Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.