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    Did you mean Wnt/β-catenin pathway?
    GlossaryWnt signaling pathway (Wnt/β-catenin pathway)

    regulates cell growth and differentiation, crucial for hair regeneration

    The Wnt signaling pathway is a complex network of proteins that play a crucial role in regulating cell growth, development, and differentiation. It is particularly important in the context of hair growth and regeneration, as it influences the activity of hair follicle stem cells. Dysregulation of this pathway can lead to conditions like alopecia or other hair growth disorders.

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      learn Estradiol

      an estrogen promoting hair regrowth more commonly used in women

      learn KY19382

      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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      community Anyone used Topical Calcipotriol (cream) or VPA ( Valproic Acid)

      in Chat  7 upvotes 3 years ago
      The conversation discusses using topical Calcipotriol and Valproic Acid for hair loss, focusing on their mechanisms involving the VDR receptor and Wnt/beta-catenin pathway. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community Hair theory Scar tissue and Verteporfin

      in Chat  26 upvotes 6 months ago
      A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Catenin signaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.

      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Cure/better treatment options in the future

      in Chat  11 upvotes 4 months ago
      The conversation is about future hair loss treatments. Current treatments mentioned include finasteride, minoxidil, and RU58841, with potential future treatments like GT20029, TDM-105795, JW0061, and follicle cloning.