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research Vitamin D receptor-mediated control of Soggy, Wise, and Hairless gene expression in keratinocytes

13 citations , November 2013 in “Journal of Endocrinology/Journal of endocrinology”

This study found that the vitamin D receptor, but not its ligand, regulates genes involved in hair cycle progression, suggesting a role in integrating hormone signaling pathways for hair and epidermal functions.

research Expression ofWise in chick embryos

6 citations , July 2007 in “Developmental Dynamics”

This study reports that Wise is expressed in specific patterns during the morphogenesis of chick embryos, particularly in regions associated with known signaling molecules like Wnt, Bmp, and Shh.

research Roles of jumonji and jumonji family genes in chromatin regulation and development

178 citations , May 2006 in “Developmental Dynamics”

This review discusses the role of jumonji family proteins in chromatin regulation and development, highlighting their involvement in transcriptional repression and histone demethylation, but reports no new experimental findings.

research Hairless and Wnt Signaling: Allies in Epithelial Stem Cell Differentiation

74 citations , September 2006 in “Cell Cycle”

This review examines the role of Hairless, a nuclear receptor corepressor, in regulating Wnt signaling during hair cycling and reports no new clinical results.

research Hairless triggers reactivation of hair growth by promoting Wnt signaling

137 citations , September 2005 in “Proceedings of the National Academy of Sciences of the United States of America”

In this study, researchers found that transgenic expression of the Hairless gene in keratinocytes can restore hair follicle regeneration in Hr-deficient mice by repressing Wise, a modulator of Wnt signaling.

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community 3800 grafts (2022) +1860 grafts (2024) | Happy with result but thinking about lowering hairline

83 upvotes 3 months ago

A user shared their positive experience with two hair transplants totaling 5660 grafts, expressing satisfaction but considering a lower hairline. They decided against further procedures after receiving advice to preserve donor hair for future needs and maintain a natural look.

community My 2600 Grafts Hair Transplant Surgery results

296 upvotes 9 months ago

A user shared their positive experience with a 2,600 grafts hair transplant surgery in India, expressing optimism about the results. The conversation also debated the necessity of medications like finasteride to maintain hair transplant results and prevent further hair loss.

community Where to buy kirkland minoxdil canada?

in Basic Questions 116 upvotes 9 months ago

The user is struggling to find a reliable source to buy Kirkland Minoxidil in Canada, expressing concerns about the legitimacy of online sellers. They mention skepticism about websites like Kirkland Minoxidil Solution and Zecoya.

community Need advice whether on starting Fin

in General 217 upvotes 1 year ago

The user is considering starting finasteride for hair loss prevention, expressing concerns about potential side effects like reduced libido and erectile dysfunction. They are currently taking saw palmetto, vitamin D, zinc, vitamin C, and biotin but are unsure if these will be effective.

community How can this be? I'm on a damn MTF regimen and still getting decimated

in Transgender 1 year ago

The conversation is about a person using minoxidil, finasteride, estrogen, and bicalutamide to combat hair loss, expressing frustration and desperation over their situation. They are advised against using female hormones and encouraged to focus on finasteride and minoxidil, with suggestions to seek therapy for mental health support.

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