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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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5 / 1000+ resultsresearch Injury Suppresses Ras Cell Competitive Advantage Through Enhanced Wild-Type Cell Proliferation
Injury boosts normal skin cell growth, reducing cancer cell advantage.
research Differential Metabolic Adaptations Define Responses of Winner and Loser Oncogenic Mutant Stem Cells in Skin Epidermis In Vivo
Mutant stem cells adapt their metabolism differently to outcompete normal cells in the skin.
research Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells
β-catenin is essential for stem cell activation and proliferation in hair follicles.
research Combinatorial Expression of Cell Cycle Regulators Is More Suitable for Immortalization Than Oncogenic Methods in Dermal Papilla Cells
Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.
research Temporary Cell Cycle Arrest in Human Scalp Hair Follicles and Their Epithelial Stem Cells by ALRN-6924: A Novel Strategy to Selectively Protect p53-Wildtype Cells Against Paclitaxel-Induced Alopecia
ALRN-6924 may prevent hair loss caused by chemotherapy.
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5 / 547 resultscommunity 1mg fin/15% minox once daily. Derma roll once a week 1.5mm. 1 yr 6m update
User shared 1.5-year progress using 1mg finasteride, 15% minoxidil daily, and derma rolling weekly. Experienced initial shedding but achieved significant hair regrowth and improvement.
community Frustrating back and forth progress
The user is experiencing fluctuating hair regrowth using oral finasteride, topical minoxidil, and microneedling, with the best results in the first four months. Suggestions include being patient through shedding cycles, considering oral minoxidil, and possibly adding dutasteride for stronger results.
community Dude had better hair at over 100 years of age than many of us at 20
Hair loss discussion mentions Native Americans' resistance to male pattern baldness and lack of facial hair. Users discuss genetics, sun exposure, and potential treatments like minoxidil and finasteride.
community PP405 Phase 2a press release with early results
PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.
community 2500-3000 grafts. 6 months post op. 1mg finasteride daily and 5% topical minoxidil bid.
A user named "Redbone2222" shares their positive experience with a hair transplant procedure of 2500-3000 grafts, along with the use of 1mg finasteride daily and 5% topical minoxidil. They express satisfaction with the results and believe that finasteride has been more effective for them than minoxidil.