research Injury suppresses Ras cell competitive advantage through enhanced wild-type cell proliferation
This study found that injury-induced proliferation of wild-type cells can suppress oncogenic growth in Ras-mosaic skin.
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5 / 1000+ resultsresearch 549 Temporary cell cycle arrest in human scalp hair follicles and their epithelial stem cells by ALRN-6924: A novel strategy to selectively protect p53-wildtype cells against paclitaxel-induced alopecia
This study found that ALRN-6924, a clinical-stage dual inhibitor, can selectively protect human scalp hair follicles from paclitaxel-induced toxicity and damage by inducing transient cell cycle arrest in healthy cells without affecting cancer cells, potentially reducing chemotherapy-induced alopecia.
research KRASG12D mutant cells are outcompeted by wild type neighbours in adult pancreas in an EPHA2-dependent manner
This study found that KrasG12D mutant cells are typically cleared from adult pancreas tissues through mechanisms involving the EphA2 receptor, suggesting its role as a tumor suppressor in pancreatic cancer.
research A Simple In Vivo System for Studying Epithelialization, Hair Follicle Formation, and Invasion Using Primary Epidermal Cells from Wild-Type and Transgenic Ornithine Decarboxylase-Overexpressing Mouse Skin
This study demonstrated that the tracheal xenotransplant procedure is an effective technique for assessing the invasiveness of epidermal keratinocytes and studying factors affecting hair follicle formation.
research Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild‐type and BK5.AktWT mice
This study found that rapamycin effectively inhibits TPA-induced keratinocyte proliferation and skin tumor promotion by targeting mTORC1 signaling in both wild-type and transgenic mice.
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5 / 458 resultscommunity Derm stopped me from using Minoxidal
A dermatologist advised stopping minoxidil due to heavy shedding, suggesting alternative treatments like Betaval Lotion and supplements, but many users disagreed, recommending continuing minoxidil and adding finasteride for better results. The conversation highlights skepticism about the dermatologist's motives and emphasizes the importance of understanding the type of hair loss before choosing treatments.
community Growing hair witch capsaicin and occasional topical minoxidil
A user shared their experience using capsaicin from chili peppers and occasional topical minoxidil to promote hair growth, noting noticeable improvements without significant side effects. They previously experienced side effects from dutasteride and minoxidil but found the new regimen effective and manageable.
community Frustrating back and forth progress
The user is experiencing fluctuating hair regrowth using oral finasteride, topical minoxidil, and microneedling, with the best results in the first four months. Suggestions include being patient through shedding cycles, considering oral minoxidil, and possibly adding dutasteride for stronger results.
community So excited! Just got dutasteride for free when I forever thought I’d have to pay! 😭
A user who was able to get dutasteride for free with their insurance, and another user mentioning that finasteride is only covered if it is used for medical reasons.
community Hair transplants and PP405 - Irregular density concern
The conversation discusses concerns about getting a hair transplant with the potential release of a new treatment, PP405, which may regrow dormant hair follicles. The user is currently using Minoxidil, Derma, and Keto but is waiting to start finasteride or dutasteride.
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2 / 801 resultslearn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
