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research Widespread and eruptive comedonal lesions with alopecia

November 2022 in “JAAD case reports”

This report diagnosed a 68-year-old man with comedonal folliculotropic mycosis fungoides based on clinical and histopathological findings, and found pegylated interferon alpha-2a with isotretinoin beneficial in reducing skin lesions.

research Recalcitrant widespread alopecia areata in a child treated successfully with oral methylprednisolone pulse therapy

July 2013 in “Our Dermatology Online”

In this case study, an 11-year-old boy with extensive alopecia areata showed 80% hair regrowth after six months of treatment with methylprednisolone despite initial lack of response to topical therapies.

research A case of widespread non-pigmented hair regrowth in diffuse alopecia areata

March 2019 in “Our Dermatology Online”

A woman with severe hair loss regrew mostly white hair after treatment.

research Low Level Laser Treatment for Patterned Hair Loss: A Systematic Review

January 2018 in “Archives of dermatology and skin care”

This systematic review found widespread support in existing literature for the effectiveness of low level laser therapy in promoting hair growth, but emphasized the need for larger case-controlled studies to confirm these results.

research Dermatologists’ Knowledge, Attitude, and Practice Pattern Toward Low-Dose Oral Minoxidil in Hair Loss in Saudi Arabia

March 2024 in “Clinical, Cosmetic and Investigational Dermatology”

Among Saudi dermatologists, this study reported widespread recognition of low-dose oral minoxidil's use for patterned hair loss and its side effect of hypertrichosis; however, many avoid prescribing it due to its unavailability in local pharmacies.

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Community Join

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community Update July 2025] Most Promising Hair Loss Treatments in Clinical Trials

in Research/Science 267 upvotes 1 year ago

Promising hair loss treatments in clinical trials include Pyrilutamide, GT20029, CB-03-01, and PP405, with potential market releases between 2027 and 2029. Hair cloning remains experimental and expensive, while existing treatments like finasteride, minoxidil, and microneedling continue to be used.

community Accelerated Hair Loss from Creatine

137 upvotes 10 months ago

Creatine may cause hair loss in some individuals, especially those on finasteride, despite no scientific link. Personal experiences suggest individual sensitivity to DHT could be a factor.

community Popular hair loss drug linked to higher suicide risk: compared to non-users, finasteride (Proscar/ Propecia) users have a markedly increased risk of depression, anxiety, and suicidal thoughts. Over 30 years of observation, 19,320 suicides were expected.

494 upvotes 11 months ago

Finasteride users may have an increased risk of depression, anxiety, and suicidal thoughts, though some attribute these issues to hair loss itself. The link between finasteride and mental health effects is debated, with varying user experiences.

community Hairloss and dandruff.. potential sebderm inflammation?

in Research/Science 1 upvotes 1 year ago

A 21-year-old is experiencing aggressive hair loss and dandruff, possibly due to seborrheic dermatitis, and is using pumpkin seed oil, scalp massages, and anti-dandruff shampoo as treatments. They are hesitant to use prescribed Finasteride and Minoxidil and have noticed some improvement after stopping Serenoa capsules.

community Nanoxidil Is Probably Better Than Minoxidil. Big Pharma Is Why You’ve Never Heard Of It.

6 months ago

Nanoxidil may be more effective than Minoxidil for hair loss due to better follicle penetration, but it lacks widespread recognition and research because it's owned by a small company and classified as a cosmetic. The pharmaceutical system favors Minoxidil due to its established market presence and profitability, leaving Nanoxidil largely unstudied and unknown.

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Learn

10 / 10 results

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Platelet-Rich Plasma

growth factors taken from your blood and injected into your scalp to stimulate hair

learn Castor oil

a traditional, natural remedy touted for promoting scalp health and hair growth

learn GT20029

research compound made to degrade androgen receptors in scalp

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

learn Hair Transplant

What causes hair loss in women that may lead to considering a hair transplant? Genetic factors, hormonal changes, stress, and nutritional deficiencies often cause hair loss in women.

learn zinc PCA

Can a zinc deficiency directly cause hair thinning or increased shedding? Studies link low serum zinc to diffuse shedding and alopecia areata, and severe deficiency states cause hair loss that reverses when zinc is replaced. The evidence is mostly observational, the one supplementation study was small and uncontrolled, and zinc is not a treatment for pattern hair loss.

learn RU58841

Will I lose my hair if I stop using RU58841? (Spoiler: I might.) There is no published human trial of stopping RU58841; community members commonly report shedding within weeks to months, and androgen biology suggests miniaturization would resume once the topical anti-androgen is withdrawn.

learn Finasteride

Does hair strand thickness decrease in men with androgenic alopecia? Can finasteride help restore it? Androgenic alopecia thins hair strands by miniaturizing follicles. The pivotal finasteride trials (1,553 men, 1 mg/day, two years) report increased hair counts and improved assessed appearance, but they measured density, not the diameter of individual strands, so the effect on thickness itself is not established.

learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

Clinics

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Experts

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SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas