research Epidermal Stem Cells and Skin Tissue Engineering in Hair Follicle Regeneration
Hair follicle regeneration needs special conditions and young cells.
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5 / 180 results research Human Wharton’s Jelly Mesenchymal Stem Cells Plasticity Augments Scar-Free Skin Wound Healing with Hair Growth
Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.
research Single-cell RNA-seq highlights heterogeneity in human primary Wharton’s jelly mesenchymal stem/stromal cells cultured in vitro
The study investigated the gene expression profiles of human primary Wharton's jelly-derived mesenchymal stem/stromal cells (WJMSCs) using single-cell RNA sequencing from three donors, revealing significant heterogeneity in their functional characteristics. Highly variable genes (HVGs) were enriched in functions related to development, signal transduction, and cell proliferation, and were associated with classic MSC functions like inflammation and angiogenesis. The study identified distinct subpopulations of MSCs with diverse functional traits, and CD142 + and CD142 − WJMSCs showed different proliferation and wound healing capacities. Despite being derived from different tissues, WJMSCs and adipose-derived MSCs shared similar HVGs, suggesting potential markers for further studies on MSC therapeutic applications.
research Wharton's Jelly-Derived Mesenchymal Stem Cells in the Treatment of Four Patients with Alopecia Areata
Wharton's jelly-derived stem cells were safely used to treat four alopecia patients, resulting in hair regrowth in all of them.
research Decellularized Wharton's Jelly Matrix as a Three Dimensional Scaffold for Wound Healing and Hair Regeneration Applications
Using Wharton's jelly stem cells and scaffolds can help regenerate skin and hair.
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